Commitments and Contingencies (Details) $ in Thousands		1 Months Ended	3 Months Ended								12 Months Ended
	Jun. 12, 2013 USD ($) ft² facility option	Dec. 31, 2014 lease	Dec. 31, 2015 USD ($) letters_of_credit	Sep. 30, 2015 USD ($)	Jun. 30, 2015 USD ($)	Mar. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Sep. 30, 2014 USD ($)	Jun. 30, 2014 USD ($)	Mar. 31, 2014 USD ($)	Dec. 31, 2015 USD ($) letters_of_credit	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
2016			$ 2,500								$ 2,500
2017			2,462								2,462
2018			2,389								2,389
2019			2,390								2,390
2020			2,500								2,500
2021 and thereafter			22,884								22,884
Total			$ 35,125								35,125
Rent expense											$ 2,300	$ 2,700	$ 600
Number of facilities | facility	2
Number of leases exited | lease		1
Term of contract	15 years
Number of renewal options | option	1
Renewal term	5 years
Minimum rentals	$ 1,900
Landlord improvement allowance	$ 6,800
Number of Offices | letters_of_credit			2								2
Operating Leases, Future Minimum Payments Due, Base Rent Increases [Abstract]
2015			3.00%								3.00%
2016			3.00%								3.00%
2017			3.00%								3.00%
2018			3.00%								3.00%
2019			3.00%								3.00%
2020 and beyond			4.00%								4.00%
Operating expenses			$ 45,483	$ 36,370	$ 36,282	$ 36,569	$ 40,539	$ 32,504	$ 32,279	$ 29,611	$ 154,704	$ 134,933	$ 109,875
Contract Termination
Operating Leases, Future Minimum Payments Due, Base Rent Increases [Abstract]
Operating expenses											$ 1,900
Office, Research and Development and Manufacturing Facilities
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Facility, area | ft²	129,000
Manufacturing Facility
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Facility, area | ft²	57,000
Administrative Office
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Facility, area | ft²	2,900