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Stock-Based Compensation (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense $ 2,550 $ 1,815 $ 7,169 $ 5,568
Cost of goods sold        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 257 240 731 643
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 252 207 737 543
Clinical and regulatory affairs        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 321 (195) 749 67
Marketing and sales        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 888 931 2,476 2,125
General and administrative        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 832 632 2,476 2,190
Total operating expenses        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense $ 2,293 $ 1,575 $ 6,438 $ 4,925