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Stock-Based Compensation (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense $ 2,140 $ 2,097 $ 3,753 $ 4,327
Cost of goods sold
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 197 227 404 377
Research and development
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 185 191 335 396
Clinical and regulatory affairs
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 365 35 262 438
Marketing and sales
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 645 1,087 1,194 1,665
General and administrative
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense 748 557 1,558 1,451
Total operating expenses
       
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated stock-based compensation expense $ 1,943 $ 1,870 $ 3,349 $ 3,950