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Stock-Based Compensation (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense $ 1,613 $ 2,230
Cost of goods sold
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense 208 150
Research and development
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense 161 205
Clinical and regulatory affairs
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense (103) 403
Marketing and sales
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense 538 578
General and administrative
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense 809 894
Total operating expenses
   
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Allocated stock-based compensation expense $ 1,405 $ 2,080