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Condensed Consolidated Statements of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Cash flows from operating activities:      
Net loss before income tax $ (35,774,000) $ (28,730,000) $ 10,653,000
Adjustments to reconcile net loss to net cash used in operating activities:      
Bad debt expense 325,000 62,000 39,000
Depreciation and amortization 2,183,000 2,729,000 2,444,000
Stock-based compensation 6,471,000 4,136,000 2,546,000
Change in fair value of contingent consideration related to acquisition 13,700,000 10,500,000 0
Gain on sale of equipment 0 (141,000) 0
Income Tax Expense (Benefit) 531,000 (86,000) (15,067,000)
Changes in operating assets and liabilities:      
Accounts receivable (8,319,000) (3,392,000) (3,909,000)
Inventories 12,000 (9,801,000) (2,964,000)
Prepaid expenses and other current assets (408,000) (153,000) (672,000)
Accounts payable 199,000 700,000 2,098,000
Accrued payroll 1,255,000 1,597,000 498,000
Accrued expenses and other current liabilities 1,304,000 189,000 243,000
Deferred rent (8,000) 8,000 (22,000)
Net cash used in operating activities (18,529,000) (22,382,000) (4,113,000)
Cash flows from investing activities:      
Purchases of property and equipment (2,238,000) (3,033,000) (861,000)
Purchases of patent license (100,000) 0 0
Cash acquired in Nellix acquisition 0 0 698,000
Business acquisition (1,156,000) 0 0
Net cash used in investing activities (3,494,000) (3,033,000) (163,000)
Cash flows from financing activities:      
Proceeds from sale of common stock under secondary offering, net of expenses 40,069,000 0 14,990,000
Proceeds from sale of common stock under employee stock purchase plan 2,369,000 1,965,000 1,118,000
Proceeds from exercise of stock options 4,992,000 5,324,000 2,347,000
Repayments of long-term debt 0 0 (79,000)
Net cash provided by financing activities 47,430,000 7,289,000 18,376,000
Effect of exchange rate changes on cash and cash equivalents (324,000) (30,000) 26,000
Net decrease in cash and cash equivalents 25,083,000 (18,156,000) 14,126,000
Cash and cash equivalents, beginning of period 20,035,000 38,191,000 24,065,000
Cash and cash equivalents, end of period 45,118,000 20,035,000 38,191,000
Supplemental disclosure of cash flow information:      
Cash paid for interest 10,000 32,000 16,000
Cash paid for legal settlement 16,000 24,000 51,000
Non-cash investing and financing activities:      
Shares issued for acquisition $ 0 $ 0 $ 19,388,000