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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2012
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs
Stock-based compensation expense included in cost of goods sold and operating expenses for years ended December 31, 2012, 2011, and 2010 was as follows:

Year Ended December 31,

2012

2011

2010
Cost of goods sold
$
597


$
209


$
188

Operating expenses:








Research and development
1,336


753


362

Clinical and regulatory affairs
320


113


15

Marketing and sales
1,558


1,097


919

General and administrative
2,641


1,740


1,168

Total operating expenses
$
5,855


$
3,703


$
2,464










Total
$
6,452


$
3,912


$
2,652

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions
The fair value of stock options granted was estimated at the date of grant using the Black-Scholes option-pricing model. The following assumptions were used to determine fair value for the stock awards granted in the applicable year:

Year Ended December 31,

2012

2011

2010
Average expected option life (in years) (a)
6.0

6.0

6.0
Volatility (b)
55.8%

56.6%

56.4%
Risk-free interest rate (c)
1.0%

2.0%

2.4%
Dividend Yield (d)
—%

—%

—%
Weighted-average grant-date fair value per stock option
$6.90

$4.55

$2.46

(a) Determined by the historical stock option exercise behavior of the Company's employees (maximum term is 10
years).
(b) Measured using weekly price observations for a period equal to stock options' expected term.
(c) Based upon the U.S. Treasury yields in effect at the end of the quarter that the options were granted (for a period equaling the stock options' expected term).
(d) The Company has never paid cash dividends on its common stock and does not expect to declare any cash dividends.
Schedule of Share-based Compensation, Stock Options, Activity
Stock option activity during the years ended December 31, 2012, and 2011 is as follows:
 
Number of
Stock Options

Weighted
Average
Exercise Price

Weighted-
Average
Remaining
Contractual
Life (Years)

Aggregate Intrinsic Value
Outstanding — January 1, 2011
5,914,884

$3.91




Granted
1,264,333

8.38




Exercised
(1,393,794)

3.84


(a)
$7,246
Forfeited
(228,889)

5.29




Expired





Outstanding — December 31, 2011
5,556,534

$4.89




Granted
756,289

13.31




Exercised
(1,167,715)

4.28


(a)
$11,135
Forfeited
(188,378)

8.32




Expired





Outstanding — December 31, 2012
4,956,730

$6.21

6.9
(b)
$39,947
Vested and Expected to Vest — December 31, 2012
4,235,058

$5.87

6.7
(b)
$35,536
Vested — December 31, 2012
2,551,156

$4.35

5.7
(b)
$25,242
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range
The following table summarizes information regarding outstanding stock option grants as of December 31, 2012:
 
 
 
Outstanding

Exercisable
Range of Exercise Prices
 
Granted
Stock Options
Outstanding

Weighted-
Average
Remaining
Contractual
Life (Years)

Weighted-
Average
Exercise
Price

Granted
Stock Options
Exercisable

Weighted-
Average
Exercise
Price
$
1.64

$
2.25

 
237,196


5.7

$
2.07


232,301


$
2.07

$
2.26

$
2.62

 
239,228


5.4

2.55


238,707


2.55

$
2.67

$
2.69

 
442,065


5.4

2.67


442,065


2.67

$
2.79

$
3.02

 
57,658


4.1

2.89


57,033


2.89

$
3.35

$
3.45

 
154,821


4.4

3.42


146,281


3.42

$
3.46

$
3.90

 
378,248


4.3

3.55


234,333


3.60

$
3.92

$
4.31

 
302,717


6.0

4.14


149,193


4.10

$
4.32

$
4.51

 
825,479


7.0

4.40


391,046


4.37

$
4.63

$
5.49

 
284,561


5.7

5.26


121,597


5.03

$
5.72

$
7.12

 
403,986


5.8

6.31


166,458


6.23

$
7.14

$
8.26

 
632,754


8.3

8.02


268,550


8.12

$
8.57

$
11.68

 
417,570


8.8

10.40


78,254


10.38

$
11.97

$
13.93

 
307,693


9.5

13.32


18,150


13.53

$
14.01

$
15.51

 
272,754


9.4

14.65


7,188


14.83

$
1.64

$
15.51

 
4,956,730


6.9

$
6.21


2,551,156


$
4.35

Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity
The following table summarizes activity and related information for the Company's restricted stock awards:


Number of
Restricted Stock Awards

Weighted Average
Fair
Value per Share at Grant Date

Grant Date Fair Value

Vest Date Fair Value*
Unvested as of December 31, 2009
685,000








      Granted
518,045


$
5.95


$
3,082




      Cancelled
(35,965
)







      Vested
(575,625
)







Unvested as of December 31, 2010
591,455








      Granted
34,000


$
6.19


$
210




      Cancelled
(6,303
)









      Vested
(35,851
)









Unvested as of December 31, 2011
583,301










Granted
475,253


$
12.67


$
6,022




Canceled
(43,598
)









Vested
(70,111
)







$
1,002

Unvested as of December 31, 2012
944,845