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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 KLhlCIzjgI85Aaeh50Stdf14ERt940QJ13hbUGcVuFy7vI1fDK6Ty3+4Jxc08kmn
 7kiET8YCG2QC5jcdR8L2Lw==

<SEC-DOCUMENT>0001291271-04-000017.txt : 20041203
<SEC-HEADER>0001291271-04-000017.hdr.sgml : 20041203
<ACCEPTANCE-DATETIME>20041203162253
ACCESSION NUMBER:		0001291271-04-000017
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20041201
FILED AS OF DATE:		20041203
DATE AS OF CHANGE:		20041203

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AAIPHARMA INC
		CENTRAL INDEX KEY:			0001013243
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-TESTING LABORATORIES [8734]
		IRS NUMBER:				042687849
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2320 SCIENTIFIC PARK DRIVE
		CITY:			WILMINGTON
		STATE:			NC
		ZIP:			28405
		BUSINESS PHONE:		9102547000

	MAIL ADDRESS:	
		STREET 1:		2320 SCIENTIFIC PARK DRIVE
		CITY:			WILMINGTON
		STATE:			NC
		ZIP:			28405

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	APPLIED ANALYTICAL INDUSTRIES INC
		DATE OF NAME CHANGE:	19960430

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CZAJKOWSKI MATTHEW E
		CENTRAL INDEX KEY:			0001208291

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-21185
		FILM NUMBER:		041184062

	MAIL ADDRESS:	
		STREET 1:		1414 RALEIGHT RD
		STREET 2:		STE 400
		CITY:			CHAPEL HILL
		STATE:			NC
		ZIP:			27517
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2004-12-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001013243</issuerCik>
        <issuerName>AAIPHARMA INC</issuerName>
        <issuerTradingSymbol>AAII</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001208291</rptOwnerCik>
            <rptOwnerName>CZAJKOWSKI MATTHEW E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1083 BURNING TREE DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CHAPEL HILL</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>27517</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Exec. VP and CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Restricted Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>50000</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2005-12-01</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-12-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Stock Options</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>145000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">50% vested upon six months anniversary of employment and 100% vested upon 12 months anniversary of employment.</footnote>
        <footnote id="F2">These options vest ratably annually over a three year period in equal increments.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>//Matthew E. Czajkowski//</signatureName>
        <signatureDate>2004-12-03</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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