Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenue:
Contract revenue - related party	$ 40	$ 4,671	$ 40	$ 23,337
Grant revenue	10	3	30	57
Total revenue	50	4,674	70	23,394
Operating expenses:
Research and development	5,836	8,880	18,522	26,995
General and administrative	1,460	1,320	4,489	4,201
Restructuring and asset impairment		2	2	9
Total operating expenses	7,296	10,202	23,013	31,205
Loss from operations	(7,246)	(5,528)	(22,943)	(7,811)
Interest income	34	7	70	22
Interest expense	(898)		(1,475)
Other expense	(76)	(28)	(653)	(68)
Net loss and comprehensive loss	$ (8,186)	$ (5,549)	$ (25,001)	$ (7,857)
Basic and diluted net loss per common share	$ (0.55)	$ (0.38)	$ (1.69)	$ (0.53)
Shares used in computing basic and diluted net loss per common share	14,782	14,751	14,774	14,743