The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERATE DIAGNOSTICS INC COM 00430H102   1,057,458 1,510,654 SH   SOLE   1,510,654 0 0
AGENUS INC COM NEW 00847G705   5,996,567 3,945,110 SH   SOLE   3,945,110 0 0
ARDELYX INC COM 039697107   3,399,463 709,700 SH   SOLE   709,700 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103   4,633,053 555,522 SH   SOLE   555,522 0 0
BIOGEN INC COM 09062X103   670,608 2,412 SH   SOLE   2,412 0 0
BIOHAVEN LTD COM G1110E107   8,680,602 635,476 SH   SOLE   635,476 0 0
CARDINAL HEALTH INC PUT 14149Y958   111,500 130,000 SH Put SOLE   130,000 0 0
CENTENE CORP DEL CALL 15135B901   370,000 175,000 SH Call SOLE   175,000 0 0
DAY ONE BIOPHARMACEUTICALS I CALL 23954D909   104,898 185,200 SH Call SOLE   185,200 0 0
DERMTECH INC COM 24984K105   3,302,612 897,449 SH   SOLE   897,449 0 0
FORIAN INC COM 34630N106   5,198,093 1,364,329 SH   SOLE   1,364,329 0 0
GENEDX HOLDINGS CORP COM CL A 81663L101   9,244,741 25,328,057 SH   SOLE   25,328,057 0 0
IMMUTEP LTD SPONSORED ADS 45257L108   2,269,347 1,350,802 SH   SOLE   1,350,802 0 0
MCKESSON CORP PUT 58155Q953   184,000 20,000 SH Put SOLE   20,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105   7,488,052 201,400 SH   SOLE   201,400 0 0
OMEGA THERAPEUTICS INC COMMON STOCK 68217N105   2,013,031 333,836 SH   SOLE   333,836 0 0
OPKO HEALTH INC CALL 68375N903   313,148 614,300 SH Call SOLE   614,300 0 0
OPKO HEALTH INC COM 68375N103   4,151,021 2,843,165 SH   SOLE   2,843,165 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   23,339,432 2,015,495 SH   SOLE   2,015,495 0 0
PROSHARES TR ULTRAPRO QQQ 74347X831   687,400 140,000 SH   SOLE   140,000 0 0
QUIDELORTHO CORP CALL 219798905   476,710 49,400 SH Call SOLE   49,400 0 0
QUIDELORTHO CORP COM 219798105   17,462,353 196,008 SH   SOLE   196,008 0 0
SERES THERAPEUTICS INC CALL 81750R902   95,000 100,000 SH Call SOLE   100,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   1,119,690 43,500 SH   SOLE   43,500 0 0
VELO3D INC COMMON STOCK 92259N104   200,364 88,266 SH   SOLE   88,266 0 0
VERTEX ENERGY INC CALL 92534K907   244,976 100,400 SH Call SOLE   100,400 0 0
VERTEX ENERGY INC COM 92534K107   494,000 50,000 SH   SOLE   50,000 0 0