0001085146-22-002187.txt : 20220516 0001085146-22-002187.hdr.sgml : 20220516 20220516160350 ACCESSION NUMBER: 0001085146-22-002187 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220331 FILED AS OF DATE: 20220516 DATE AS OF CHANGE: 20220516 EFFECTIVENESS DATE: 20220516 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORACLE INVESTMENT MANAGEMENT INC CENTRAL INDEX KEY: 0001012622 IRS NUMBER: 133709517 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-05592 FILM NUMBER: 22928666 BUSINESS ADDRESS: STREET 1: 177 W PUTNAM AVENUE CITY: GREENWICH STATE: CT ZIP: 06830 BUSINESS PHONE: 202-862-1660 MAIL ADDRESS: STREET 1: 177 W PUTNAM AVENUE CITY: GREENWICH STATE: CT ZIP: 06830 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001012622 XXXXXXXX 03-31-2022 03-31-2022 false ORACLE INVESTMENT MANAGEMENT INC

177 W PUTNAM AVENUE GREENWICH CT 06830

13F HOLDINGS REPORT 028-05592 N Mitchell Vogel 203-862-7900 /s/ Mitchell Vogel Greenwich CT 05-16-2022 0 32 505716 false INFORMATION TABLE 2 infotable.xml INFORMATION TABLE ACADIA PHARMACEUTICALS INC COM 004225108 4524 186789 SH SOLE 186789 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 1058 459300 SH Put SOLE 459300 0 0 ACCELERATE DIAGNOSTICS INC COM 00430H102 3934 2731856 SH SOLE 2731856 0 0 AGENUS INC COM NEW 00847G705 21417 8706132 SH SOLE 8706132 0 0 ANTARES PHARMA INC COM 036642106 7052 1720000 SH SOLE 1720000 0 0 ARBUTUS BIOPHARMA CORP COM 03879J100 149 50000 SH SOLE 50000 0 0 ARK ETF TR INNOVATION ETF 00214Q104 16573 250000 SH SOLE 250000 0 0 ASPIRA WOMENS HEALTH INC COM 04537Y109 2202 2116839 SH SOLE 2116839 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 27979 1720733 SH SOLE 1720733 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 1263 550000 SH Put SOLE 550000 0 0 BIOGEN INC COM 09062X103 508 2412 SH SOLE 2412 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 244420 2061402 SH SOLE 2061402 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 212 20000 SH Put SOLE 20000 0 0 CENTENE CORP DEL COM 15135B101 1485 300000 SH Put SOLE 300000 0 0 CODIAK BIOSCIENCES INC COM 192010106 3164 504602 SH SOLE 504602 0 0 CONTRAFECT CORP COM NEW 212326300 7133 1954222 SH SOLE 1954222 0 0 DERMTECH INC COM 24984K105 9585 652907 SH SOLE 652907 0 0 DERMTECH INC COM 24984K105 921 193800 SH Put SOLE 193800 0 0 DIREXION SHS ETF TR SP BIOTCH BL NEW 25490K323 1775 1000000 SH Put SOLE 1000000 0 0 FORIAN INC COM 34630N106 8784 1262040 SH SOLE 1262040 0 0 IMMUNITYBIO INC COM 45256X103 2244 400013 SH SOLE 400013 0 0 IMMUTEP LTD SPONSORED ADS 45257L108 2675 976156 SH SOLE 976156 0 0 OPKO HEALTH INC COM 68375N103 30911 8985756 SH SOLE 8985756 0 0 OPKO HEALTH INC COM 68375N103 292 749900 SH Put SOLE 749900 0 0 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 11151 1225395 SH SOLE 1225395 0 0 PFIZER INC COM 717081103 1265 550000 SH Put SOLE 550000 0 0 PROTAGENIC THERAPEUTICS INC COM 74365N103 16 20000 SH SOLE 20000 0 0 QUIDEL CORP COM 74838J101 79693 708631 SH SOLE 708631 0 0 QUIDEL CORP COM 74838J101 200 26500 SH Put SOLE 26500 0 0 SEMA4 HOLDINGS CORP COM CL A 81663L101 12111 3944832 SH SOLE 3944832 0 0 SOLENO THERAPEUTICS INC COM NEW 834203200 475 2132000 SH SOLE 2132000 0 0 VERTEX ENERGY INC COM 92534K107 547 55000 SH SOLE 55000 0 0