0001085146-22-001109.txt : 20220214 0001085146-22-001109.hdr.sgml : 20220214 20220214164129 ACCESSION NUMBER: 0001085146-22-001109 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20211231 FILED AS OF DATE: 20220214 DATE AS OF CHANGE: 20220214 EFFECTIVENESS DATE: 20220214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: ORACLE INVESTMENT MANAGEMENT INC CENTRAL INDEX KEY: 0001012622 IRS NUMBER: 133709517 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-05592 FILM NUMBER: 22633468 BUSINESS ADDRESS: STREET 1: 177 W PUTNAM AVENUE CITY: GREENWICH STATE: CT ZIP: 06830 BUSINESS PHONE: 202-862-1660 MAIL ADDRESS: STREET 1: 177 W PUTNAM AVENUE CITY: GREENWICH STATE: CT ZIP: 06830 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001012622 XXXXXXXX 12-31-2021 12-31-2021 false ORACLE INVESTMENT MANAGEMENT INC

177 W PUTNAM AVENUE GREENWICH CT 06830

13F HOLDINGS REPORT 028-05592 N Mitchell Vogel 203-862-7900 /s/ Mitchell Vogel Greenwich CT 02-14-2022 0 32 703730 false INFORMATION TABLE 2 infotable.xml INFORMATION TABLE ACCELERATE DIAGNOSTICS INC COM 00430H102 18936 3627549 SH SOLE 3627549 0 0 AGENUS INC COM NEW 00847G705 29322 9106132 SH SOLE 9106132 0 0 AGENUS INC COM NEW 00847G705 22 298300 SH Put SOLE 298300 0 0 ANTARES PHARMA INC COM 036642106 6140 1720000 SH SOLE 1720000 0 0 ARK ETF TR GENOMIC REV ETF 00214Q302 1076 350000 SH Put SOLE 350000 0 0 ASPIRA WOMENS HEALTH INC COM 04537Y109 9818 5547094 SH SOLE 5547094 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 23140 1670733 SH SOLE 1670733 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 1383 700000 SH Put SOLE 700000 0 0 BIOGEN INC COM 09062X103 579 2412 SH SOLE 2412 0 0 BIOHAVEN PHARMACTL HLDG CO L COM G11196105 286011 2075402 SH SOLE 2075402 0 0 CENTENE CORP DEL COM 15135B101 531 416300 SH Put SOLE 416300 0 0 CODIAK BIOSCIENCES INC COM 192010106 7343 659191 SH SOLE 659191 0 0 CONTRAFECT CORP COM NEW 212326300 5135 1952422 SH SOLE 1952422 0 0 CROSS CTRY HEALTHCARE INC COM 227483104 1971 71000 SH SOLE 71000 0 0 DERMTECH INC COM 24984K105 9526 602907 SH SOLE 602907 0 0 DERMTECH INC COM 24984K105 425 250000 SH Put SOLE 250000 0 0 FORIAN INC COM 34630N106 11001 1219661 SH SOLE 1219661 0 0 IMMUTEP LTD SPONSORED ADS 45257L108 3202 976156 SH SOLE 976156 0 0 MOTUS GI HLDGS INC COM 62014P108 49 105885 SH SOLE 105885 0 0 OPKO HEALTH INC COM 68375N103 58774 12219073 SH SOLE 12219073 0 0 OPKO HEALTH INC COM 68375N103 685 757300 SH Put SOLE 757300 0 0 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 29120 1420652 SH SOLE 1420652 0 0 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 126 67000 SH Put SOLE 67000 0 0 PFIZER INC COM 717081103 28049 475000 SH SOLE 475000 0 0 PFIZER INC COM 717081103 15041 1400000 SH Put SOLE 1400000 0 0 PROTAGENIC THERAPEUTICS INC COM 74365N103 416 300267 SH SOLE 300267 0 0 QUIDEL CORP COM 74838J101 115426 855068 SH SOLE 855068 0 0 SOLENO THERAPEUTICS INC COM NEW 834203200 874 2132000 SH SOLE 2132000 0 0 SPDR S&P 500 ETF TR TR UNIT 78462F103 1308 500000 SH Put SOLE 500000 0 0 VIR BIOTECHNOLOGY INC COM 92764N102 36050 861008 SH SOLE 861008 0 0 VIR BIOTECHNOLOGY INC COM 92764N102 1577 287600 SH Put SOLE 287600 0 0 XBIOTECH INC COM 98400H102 674 500000 SH Put SOLE 500000 0 0