The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERATE DIAGNOSTICS INC COM 00430H102 808 180,000 SH Call SOLE   180,000 0 0
ACCELERATE DIAGNOSTICS INC COM 00430H102 99,674 4,356,363 SH   SOLE   4,356,363 0 0
AGENUS INC COM NEW 00847G705 4,227 1,408,918 SH   SOLE   1,408,918 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 99,451 5,128,970 SH   SOLE   5,128,970 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 478 650,700 SH Call SOLE   650,700 0 0
BIOGEN INC COM 09062X103 1,489 6,368 SH   SOLE   6,368 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 73,258 1,672,950 SH   SOLE   1,672,950 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 692 458,800 SH Call SOLE   458,800 0 0
BIOLASE INC COM NEW 090911207 7,605 5,173,250 SH   SOLE   5,173,250 0 0
CIGNA CORP NEW COM 125523100 4,672 29,653 SH   SOLE   29,653 0 0
CONTRAFECT CORP COM 212326102 3,242 6,356,649 SH   SOLE   6,356,649 0 0
DERMIRA INC COM 24983L104 16,826 1,760,072 SH   SOLE   1,760,072 0 0
MOTUS GI HLDGS INC COM 62014P108 11,413 3,766,666 SH   SOLE   3,766,666 0 0
OPKO HEALTH INC COM 68375N103 8,994 3,686,194 SH   SOLE   3,686,194 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 6,720 1,110,666 SH   SOLE   1,110,666 0 0
QUIDEL CORP COM 74838J101 105,902 1,785,264 SH   SOLE   1,785,264 0 0
SOLENO THERAPEUTICS INC COM NEW 834203200 10,678 3,813,558 SH   SOLE   3,813,558 0 0
VERMILLION INC COM NEW 92407M206 8,745 9,825,289 SH   SOLE   9,825,289 0 0