The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERATE DIAGNOSTICS INC COM 004304200 140,042 5,425,893 SH   SOLE   5,425,893 0 0
ACCURAY INC COM 004397105 21,412 3,176,838 SH   SOLE   3,176,838 0 0
ACORDA THERAPEUTICS INC COM 00484M106 27,192 815,838 SH   SOLE   815,838 0 0
AGENUS INC COM 00847G101 30,892 3,579,592 SH   SOLE   3,579,592 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 12,753 5,184,225 SH   SOLE   5,184,225 0 0
BIOGEN INC COM 09062X103 3,120 7,723 SH   SOLE   7,723 0 0
BIOLASE INC COM 090911108 18,226 10,474,725 SH   SOLE   10,474,725 0 0
CHIMERIX INC COM 16934W106 47,398 1,025,921 SH   SOLE   1,025,921 0 0
CONTRAFECT CORP COM 212326102 6,206 1,182,032 SH   SOLE   1,182,032 0 0
HANSEN MEDICAL INC COM 411307101 41,100 44,918,191 SH   SOLE   44,918,191 0 0
INTREXON CORP COM 46122T102 42,773 876,502 SH   SOLE   876,502 0 0
LADENBURG THALMAN FIN SVCS I COM 50575Q102 210 60,000 SH   SOLE   60,000 0 0
MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 32,466 2,439,237 SH   SOLE   2,439,237 0 0
METABOLIX INC COM 591018809 4,326 1,153,592 SH   SOLE   1,153,592 0 0
NXSTAGE MEDICAL INC COM 67072V103 51,040 3,572,963 SH   SOLE   3,572,963 0 0
OPKO HEALTH INC COM 68375N103 79,746 4,959,335 SH   SOLE   4,959,335 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 18,673 3,241,761 SH   SOLE   3,241,761 0 0
QUIDEL CORP COM 74838J101 66,459 2,895,808 SH   SOLE   2,895,808 0 0
RAPTOR PHARACEUTICALS COM 045685659 44,920 2,844,815 SH   SOLE   2,844,815 0 0
REGULUS THERAPEUTICS INC COM 75915K101 8,130 741,804 SH   SOLE   741,804 0 0
SECOND SIGHT MED PRODS INC COM 81362J100 2,859 210,000 SH   SOLE   210,000 0 0
TESARO INC COM 881569107 28,983 493,000 SH   SOLE   493,000 0 0
THORATEC CORP COM NEW 885175307 54,803 1,229,600 SH   SOLE   1,229,600 0 0
TRANSITION THERAPEUTICS INC COM NEW 893716209 10,214 4,863,914 SH   SOLE   4,863,914 0 0
VERMILLION INC COM NEW 92407M206 16,792 8,112,182 SH   SOLE   8,112,182 0 0
WEBMD HEALTH CORP COM 94770V102 10,543 238,103 SH   SOLE   238,103 0 0
ZIOPHARM ONCOLOGY INC COM 98973P101 2,906 242,168 SH   SOLE   242,168 0 0