The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERATE DIAGNOSTICS INC COM 004304200 122,083 5,425,893 SH   SOLE   5,425,893 0 0
ACCURAY INC COM 004397105 31,306 3,366,216 SH   SOLE   3,366,216 0 0
ACORDA THERAPEUTICS INC COM 00484M106 34,770 1,044,783 SH   SOLE   1,044,783 0 0
AGENUS INC COM 00847G101 5,977 1,165,184 SH   SOLE   1,165,184 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 12,008 5,131,444 SH   SOLE   5,131,444 0 0
BIOGEN INC COM 09062X103 3,261 7,723 SH   SOLE   7,723 0 0
BIOLASE INC COM 090911108 21,159 10,474,725 SH   SOLE   10,474,725 0 0
CERUS CORP COM 157085101 2,752 659,900 SH   SOLE   659,900 0 0
CHIMERIX INC COM 16934W106 36,329 963,898 SH   SOLE   963,898 0 0
HANSEN MEDICAL INC COM 411307101 22,644 26,027,981 SH   SOLE   26,027,981 0 0
INTREXON CORP COM 46122T102 31,423 692,594 SH   SOLE   692,594 0 0
LADENBURG THALMAN FIN SVCS I COM 50575Q102 432 111,789 SH   SOLE   111,789 0 0
MAZOR ROBOTICS LTD SPONSORED ADS 57886P103 24,687 2,198,270 SH   SOLE   2,198,270 0 0
METABOLIX INC COM 591018809 4,500 7,258,106 SH   SOLE   7,258,106 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 2,248 147,895 SH   SOLE   147,895 0 0
NXSTAGE MEDICAL INC COM 67072V103 64,950 3,754,343 SH   SOLE   3,754,343 0 0
OPKO HEALTH INC COM 68375N103 70,276 4,959,335 SH   SOLE   4,959,335 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 19,183 3,284,796 SH   SOLE   3,284,796 0 0
PLASMATECH BIOPHARMACEUTICAL COM 72754H109 4,236 1,348,960 SH   SOLE   1,348,960 0 0
QUIDEL CORP COM 74838J101 78,664 2,915,633 SH   SOLE   2,915,633 0 0
RAPTOR PHARACEUTICALS COM 045685659 29,165 2,683,093 SH   SOLE   2,683,093 0 0
REGULUS THERAPEUTICS INC COM 75915K101 21,804 1,287,150 SH   SOLE   1,287,150 0 0
SECOND SIGHT MED PRODS INC COM 81362J100 2,692 210,000 SH   SOLE   210,000 0 0
TESARO INC COM 881569107 31,936 556,379 SH   SOLE   556,379 0 0
THORATEC CORP COM NEW 885175307 51,634 1,232,600 SH   SOLE   1,232,600 0 0
TRANSITION THERAPEUTICS INC COM NEW 893716209 33,203 4,861,321 SH   SOLE   4,861,321 0 0
VERMILLION INC COM NEW 92407M206 14,359 8,112,182 SH   SOLE   8,112,182 0 0
WEBMD HEALTH CORP COM 94770V102 10,437 238,103 SH   SOLE   238,103 0 0