Income Taxes (Details Textual) - USD ($)		1 Months Ended	12 Months Ended
	Mar. 08, 2017	Dec. 31, 2014	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Taxes [Line Items]
Statutory tax rate			12.50%	33.30%	33.30%
Increase (decrease) in income tax provision			$ (4,349,000)	$ 36,551,000
Income tax provision effect of cross-border merger			9,773,000	0	$ 0
Income tax provision effect of transfer of intellectual property			938,000	980,000	15,273,000
Reasonably possible change in amount of unrecorded benefit in next twelve months			250,000
Reasonably possible change in amount of interest and penalties in next twelve months			50,000
Unrecognized tax benefits that would impact effective tax rate		$ 0	1,565,000	291,000	0
Income tax penalties and interest expense			26,000	0	0
Income tax penalties and interest accrued			27,000	0
Deferred tax assets, tax credit carryforwards, research			1,775,000	2,382,000
Gross research tax credit			3,376,000	3,720,000
Research tax credit utilized			4,001,000
Current deferred tax liabilities			1,601,000	1,338,000
Income tax charge			31,558,000	35,907,000	(644,000)
Tax-related prepaid expenses		986,000	814,000	842,000	986,000
Deferred tax assets		$ 13,102,000	10,342,000	11,581,000	$ 13,102,000
Income tax deferred charge			11,156,000
Deferred tax amortized rate		7.00%
Income tax provision related to cross-border merger			$ 4,001,000
Subsequent Event
Income Taxes [Line Items]
Potential income tax benefit based on impact of ruling	$ 3,848,000
Potential research and development tax credit based on impact of ruling	2,582,000
Potential release of unrecognized tax benefits based on impact of ruling	$ 1,266,000
Ireland
Income Taxes [Line Items]
Statutory tax rate			12.50%
Net operating loss carryforwards			$ 45,907,000
Net operating loss carryforwards valuation allowance			5,738,000	$ 3,628,000
Tax relief amount			8,500,000
France
Income Taxes [Line Items]
Statutory tax rate				33.30%	33.30%
Net operating loss carryforwards valuation allowance				$ 40,959,000
Income tax charge		$ 14,088,000
Removal of operating loss carryforwards			111,495,000
United States
Income Taxes [Line Items]
Net operating loss carryforwards			14,920,000
Net operating loss carryforwards valuation allowance			$ 1,272,000