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Summary of Significant Accounting Policies - Revenue (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Change in Accounting Estimate [Line Items]
Product sales and services	$ 147,222	$ 172,288	$ 12,193
Effect on earnings per diluted share (in usd per share)	$ (1.00)	$ 0.96	$ (2.47)
License and research revenue	$ 3,024	$ 721	$ 2,782
Change in Accounting Method Accounted for as Change in Estimate
Change in Accounting Estimate [Line Items]
Product sales and services	$ 5,981
Effect on earnings per diluted share (in usd per share)	$ 0.05

The amount of net income (loss) derived from continuing operations during the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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