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Summary of Significant Accounting Policies - Property and Equipment Useful Lives (Details)
12 Months Ended
Dec. 31, 2016
Laboratory equipment | Maximum  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful lives P8Y
Laboratory equipment | Minimum  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful lives P4Y
Office and computer equipment  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful lives P3Y
Furniture, fixtures and fittings | Maximum  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful lives P10Y
Furniture, fixtures and fittings | Minimum  
Property, Plant and Equipment [Line Items]  
Property and equipment, estimated useful lives P5Y