Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2016

Accounting Policies [Abstract]

Schedule of Error Corrections and Prior Period Adjustments

The impact of the above errors and reclassifications on previously presented line items for each comparative period presented is as follows: 

	Twelve Months Ended December 31, 2014
				Correction of Immaterial Errors
Consolidated Statement of Loss:	As filed			(b)		(f)			As revised
Product sales and services	$	11,993		$	200	$	—		$	12,193
Total revenue	14,775			200		—			14,975
Operating income (loss)	(93,857		)	200		—			(93,657		)
Income (loss) before income taxes	(90,331		)	200		—			(90,131		)
Income tax provision (benefit)	(1,407		)	70		693			(644		)
Net income (loss) from continuing operations	(88,924		)	130		(693		)	(89,487		)
Net income (loss)	(84,906		)	130		(693		)	(85,469		)
Net loss per share - basic	$	(2.34	)	$	—	$	(0.02	)	$	(2.36	)
Net loss per share - diluted	$	(2.34	)	$	—	$	(0.02	)	$	(2.36	)

	Twelve Months Ended December 31, 2015
			Correction of Immaterial Errors
Consolidated Statement of Income:	As filed		(a)			(b)			(c)			As revised
Product sales and services	$	172,488	$	—		$	(200	)	$	—		$	172,288
Total revenue	173,209		—			(200		)	—			173,009
Cost of products and services sold	10,921		—			—			489			11,410
Total operating expenses	101,762		—			—			489			102,251
Operating income (loss)	71,447		—			(200		)	(489		)	70,758
Income (loss) before income taxes	78,394		—			(200		)	(489		)	77,705
Income tax provision (benefit)	37,735		(1,587		)	(70		)	(171		)	35,907
Net income (loss) from continuing operations	40,659		1,587			(130		)	(318		)	41,798
Net income (loss)	40,659		1,587			(130		)	(318		)	41,798
Net income (loss) per share - basic	$	1.00	$	0.04		$	—		$	(0.01	)	1.03
Net income (loss) per share - diluted	$	0.93	$	0.04		$	—		$	(0.01	)	$	0.96

	December 31, 2015
				Correction of Immaterial Errors									Reclassifications
Consolidated Balance Sheet:	As filed			(a)			(c)			(d)			(e)			(g)		As revised
Accounts receivable	$	6,978		$	—		$	—		$	—		$	509		$	—	$	7,487
Inventories	4,155			—			(489		)	—			—			—		3,666
Prepaid expenses and other current assets	7,989			—			—			—			—			75		8,064
Total current assets	166,306			—			(489		)	—			509			75		166,401
Other	158			—			—			—			—			9		167
Total assets	214,977			—			(489		)	—			509			84		215,081
Current portion of long-term related party payable	28,614			—			—			(3,410		)	—			—		25,204
Accounts payable	10,565			—			—			—			(5,517		)	—		5,048
Accrued expenses	3,598			—			—			—			5,710			—		9,308
Income taxes	323			(228		)	(171		)	—			—			76		—
Total current liabilities	48,788			(228		)	(171		)	(3,410		)	193			76		45,248
Long-term related party payable	94,079			—			—			3,410			—			—		97,489
Deferred taxes	1,351			(1,359		)	—			—			—			8		—
Other	2,210			—			—			—			316			—		2,526
Total liabilities	147,112			(1,587		)	(171		)	—			509			84		145,947
Accumulated deficit	(279,793		)	1,587			(318		)	—			—			—		(278,524		)
Total shareholders' equity	67,865			1,587			(318		)	—			—			—		69,134
Total liabilities and shareholders' equity	214,977			—			(489		)	—			509			84		215,081

(a) Reflects the cumulative 2015 correction of $1,587 of income tax benefits related to the deductibility of the U.S. Internal Revenue Code Section 483 imputed interest on contingent consideration liabilities which should have been recorded in prior periods ($866, $292, $863 and ($434) in the first, second, third and fourth quarters of 2015, respectively).

(b) Reflects the correction of a $200 overstatement of revenue in the first quarter of 2015 resulting from errors in certain estimates of ending inventory amounts at our wholesalers which were originally corrected in the first quarter of 2015 but should have been recorded in the fourth quarter of 2014. As this item was originally corrected in the first quarter of 2015, no adjustment was required to correct the consolidated balance sheet at December 31, 2015.

(c) Reflects the correction of a $489 error in the Company’s inventory obsolescence reserve accrual and expense which was originally recorded in the first quarter of 2016 but should have been recorded in the fourth quarter of 2015.

(d) Reflects the correction of a balance sheet classification error which overstated the current portion of the long-term related party payable by $3,410.

(e) Reflects revisions to the presentation of certain gross to net revenue reserves which were previously included in accounts payable and are now included in accrued expenses.

(f) Reflects the correction of $2,606 of income tax benefits from stock-based compensation and certain other items which were originally recorded in the fourth quarter of 2015 but should have been recorded in prior periods ($360 in 2012, $333 in 2013, $(693) in 2014, and $830, $1,026 and $750 in the first, second and third quarters of 2015, respectively). As these items were originally corrected in the fourth quarter of 2015, no adjustment was required to correct the consolidated balance sheet at December 31, 2015.

(g) Reflects balance sheet reclassifications required to properly net the accrued income tax and deferred income tax amounts within the balance sheet as a result of the adjustments made in items (a) through (f) above.

Schedule of Property and Equipment Useful Life

Property and equipment is stated at historical cost less accumulated depreciation. Depreciation and amortization are computed using the straight-line method over the following estimated useful lives:

Laboratory equipment	4-8 years
Office and computer equipment	3 years
Leasehold improvements, furniture, fixtures and fittings	5-10 years

The principal categories of property and equipment, net at December 31, 2016 and 2015, respectively, are as follows:

Property and Equipment, net:	2016			2015
Laboratory equipment	$	9,019		$	9,963
Office and computer equipment	2,519			2,968
Furniture, fixtures and fittings	4,239			4,315
Less - accumulated depreciation	(12,457		)	(14,630		)
Total	$	3,320		$	2,616