Company Operations by Product, Customer and Geographic Area - Revenue by Product (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Segment Reporting Information [Line Items]
Total product sales and services	$ 147,222	$ 172,288	$ 12,193
License and research revenue	3,024	721	2,782
Total	150,246	173,009	14,975
Bloxiverz
Segment Reporting Information [Line Items]
Total product sales and services	82,896	150,083	10,411
Vazculep
Segment Reporting Information [Line Items]
Total product sales and services	39,796	20,151	0
Akovaz
Segment Reporting Information [Line Items]
Total product sales and services	16,831	0	0
Other
Segment Reporting Information [Line Items]
Total product sales and services	$ 7,699	$ 2,054	$ 1,782