-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 JOfVUltmfBkWwpWAOibcjKsDQhf1L3FkMKTkH5wFTIUSPcND1YdZjVn9Zq/vEj16
 OWpRDEnaZRO0RYSVAMxZtA==

<SEC-DOCUMENT>0001181431-05-037260.txt : 20050629
<SEC-HEADER>0001181431-05-037260.hdr.sgml : 20050629
<ACCEPTANCE-DATETIME>20050629132603
ACCESSION NUMBER:		0001181431-05-037260
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050615
FILED AS OF DATE:		20050629
DATE AS OF CHANGE:		20050629

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COLLAGENEX PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0001012270
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				521758016
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		41 UNIVERSITY DRIVE
		CITY:			NEWTON
		STATE:			PA
		ZIP:			18940
		BUSINESS PHONE:		2155797388

	MAIL ADDRESS:	
		STREET 1:		41 UNIVERSITY DRIVE
		CITY:			NEWTON
		STATE:			PA
		ZIP:			18940

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			DAVERMAN JAMES E
		CENTRAL INDEX KEY:			0001033489

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-28308
		FILM NUMBER:		05923613

	BUSINESS ADDRESS:	
		STREET 1:		500 CORPORATE CENTRE
		STREET 2:		520 LAKE COOK ROAD SUITE 450
		CITY:			DEERFIELD
		STATE:			IL
		ZIP:			60015
		BUSINESS PHONE:		215-579-7388

	MAIL ADDRESS:	
		STREET 1:		C/O COLLAGENEX PHARMACEUTICALS, INC
		STREET 2:		41 UNIVERSITY DRIVE, SUITE 200
		CITY:			NEWTOWN
		STATE:			PA
		ZIP:			18940
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>rrd83466.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2005-06-15</periodOfReport>

    <dateOfOriginalSubmission>2005-06-16</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001012270</issuerCik>
        <issuerName>COLLAGENEX PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>CGPI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001033489</rptOwnerCik>
            <rptOwnerName>DAVERMAN JAMES E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O COLLAGENEX PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>41 UNIVERSITY DRIVE, SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>NEWTOWN</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>18940</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <transactionDate>
                <value>2005-06-15</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>20000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>5.0325</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>75000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This Amendment is being filed to report the acquisition of shares of Common Stock by the filing person on June 15, 2005 as an open market purchase.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ James E Daverman</signatureName>
        <signatureDate>2005-06-29</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----