Exhibit 23.1

                          Independent Auditors' Consent



The Board of Directors
CollaGenex Pharmaceuticals, Inc.:

We consent to  incorporation  by reference in the  registration  statements  No.
333-31229 and No. 333-73230 on Form S-8 of CollaGenex Pharmaceuticals,  Inc. and
registration  statements  No.  333-88697,  No.  333-35634,  No.  333-53766,  No.
333-58568,   No.  333-67044,  and  No.  333-72166  on  Form  S-3  of  CollaGenex
Pharmaceuticals,  Inc. of our report dated  January 31,  2001,  except as to the
first  paragraph  of note  14,  which  is as of March  12,  2001 and the  second
paragraph  of note 14,  which is as of  March  19,  2001,  with  respect  to the
consolidated balance sheets of CollaGenex Pharmaceuticals, Inc. and subsidiaries
as of December 31, 1999 and 2000,  and the related  consolidated  statements  of
operations,  stockholders'  equity  and cash  flows for each of the years in the
three-year period ended December 31, 2000, and the related  financial  statement
schedule,  which report  appears in the December 31, 2000 Annual  Report on Form
10-K/A of  CollaGenex  Pharmaceuticals,  Inc. Our report refers to the Company's
adoption of the  provisions of the Securities  and Exchange  Commission's  Staff
Accounting  Bulletin No. 101, "Revenue  Recognition in Financial  Statements" in
2000.

                                  /s/ KPMG LLP

Princeton, New Jersey
January 2, 2002