X0303 4 2009-03-31 0 0001012140 ONYX PHARMACEUTICALS INC ONXX 0001282660 WOOD JULIANNA R C/O ONYX PHARMACEUTICALS, INC. 2100 POWELL ST., 12TH FLOOR EMERYVILLE CA 94608 0 1 0 0 VP, Corp. Communication/I.R. Common Stock 2009-03-31 4 A 0 3750 0.00 A 12083 D Common Stock 2009-04-01 4 S 0 1211 27.90 D 10872 D Common Stock 2009-04-01 4 S 0 11 27.45 D 10861 D Common Stock 2009-04-01 4 S 0 11 27.54 D 10850 D Common Stock 200 I Children's Trust Stock Option (Right to Buy) 28.55 2009-03-31 4 A 0 26250 0.00 A 2019-03-31 Common Stock 26250 26250 D Shares sold pursuant to a 10b5-1 plan. 12.5% of the shares subject to the option become exercisable 6 months following the date of grant. The remaining shares become exercisable in equal monthly installments over the following 42 months for a total vesting schedule of 48 months. /s/ Matthew K. Fust, Attorney-in-fact 2009-04-02