X0202 4 2004-07-19 0 0001012140 ONYX PHARMACEUTICALS INC ONXX 0001187333 RENTON HOLLINGS C/O ONYX PHARMACEUTICALS, INC. 3031 RESEARCH DR., BLDG. A RICHMOND CA 94806 1 1 0 0 President and CEO Common Stock 2004-07-19 4 S 0 691 36.95 D 56681 I Family Trust Common Stock 2004-07-19 4 S 0 1609 37.00 D 55072 I Family Trust Common Stock 2004-07-19 4 S 0 200 37.02 D 54872 I Family Trust Reporting person is deemed to beneficially own an additional (i) 1,200 shares held by his spouse and (ii) 6,150 shares held directly by the reporting person. /s/ Marilyn E. Wortzman, Attorney-in-Fact 2004-07-21