-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, W2jw2oO9bcqWlq8kZKsUCmvK2FD12Ga9ZKx9hy80d15lQPWP7J+VcBo0uM2eV1Rh yOVcU+RUJe/DD2GDqFk9FQ== 0001144204-08-012681.txt : 20080229 0001144204-08-012681.hdr.sgml : 20080229 20080229163813 ACCESSION NUMBER: 0001144204-08-012681 CONFORMED SUBMISSION TYPE: SC 13G PUBLIC DOCUMENT COUNT: 3 FILED AS OF DATE: 20080229 DATE AS OF CHANGE: 20080229 GROUP MEMBERS: D. E. SHAW & CO., L.P. GROUP MEMBERS: DAVID E. SHAW SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: ONYX PHARMACEUTICALS INC CENTRAL INDEX KEY: 0001012140 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 943154463 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G SEC ACT: 1934 Act SEC FILE NUMBER: 005-45955 FILM NUMBER: 08656334 BUSINESS ADDRESS: STREET 1: 2100 POWELL STREET CITY: EMERYVILLE STATE: CA ZIP: 94608 BUSINESS PHONE: 5105976500 MAIL ADDRESS: STREET 1: 2100 POWELL STREET CITY: EMERYVILLE STATE: CA ZIP: 94608 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: D. E. Shaw Valence Portfolios, L.L.C. CENTRAL INDEX KEY: 0001294704 IRS NUMBER: 134046559 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G BUSINESS ADDRESS: STREET 1: 39TH FLOOR, TOWER 45 STREET 2: 120 WEST FORTY-FIFTH STREET CITY: NEW YORK STATE: NY ZIP: 10036 BUSINESS PHONE: (212) 478-0000 MAIL ADDRESS: STREET 1: 39TH FLOOR, TOWER 45 STREET 2: 120 WEST FORTY-FIFTH STREET CITY: NEW YORK STATE: NY ZIP: 10036 SC 13G 1 v105465_sc13g.htm
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934 
 
 
Onyx Pharmaceuticals, Inc.
(Name of Issuer)


Common Stock, $0.001 par value
(Title of Class of Securities)


683399109
(CUSIP Number)


February 19, 2008
(Date of Event Which Requires Filing of this Statement)
 
Check the following box to designate the rule pursuant to which the Schedule is filed:

o
Rule 13d-1(b)
 
x
Rule 13d-1(c)
 
o
Rule 13d-1(d)
 

* The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


 

CUSIP No. 683399109
 
 
 
1.
Names of Reporting Persons
I.R.S. Identification Nos. of above persons (entities only)
D. E. Shaw Valence Portfolios, L.L.C.
13-4046559
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
   
(a)
o
     
   
(b)
o
     
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
Delaware
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
-0-
 
       
     
6.
Shared Voting Power
4,261,870
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
4,261,870
 
           
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
4,261,870
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
       
 
11.
Percent of Class Represented by Amount in Row (9)
7.7%
 
       
 
12.
Type of Reporting Person (See Instructions)
OO
 

 

CUSIP No. 683399109
 
 
 
1.
Names of Reporting Persons
I.R.S. Identification Nos. of above persons (entities only)
D. E. Shaw & Co., L.P.
13-3695715
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
   
(a)
o
 
   
(b)
o
 
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
Delaware
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
-0-
 
       
     
6.
Shared Voting Power
4,339,468
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
4,374,668
 
           
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
4,374,668
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
       
 
11.
Percent of Class Represented by Amount in Row (9)
7.9%
 
       
 
12.
Type of Reporting Person (See Instructions)
IA, PN
 
 

 
 
CUSIP No. 683399109
 
   
 
1.
Names of Reporting Persons
I.R.S. Identification Nos. of above persons (entities only)
David E. Shaw
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
   
(a)
o
 
 
   
(b)
o
   
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
United States
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
-0-
 
       
     
6.
Shared Voting Power
4,339,468
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
4,374,668
 
 
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
4,374,668
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
       
 
11.
Percent of Class Represented by Amount in Row (9)
7.9%
 
       
 
12.
Type of Reporting Person (See Instructions)
IN
 

 
 
Item 1.
   
(a)
 
Name of Issuer:
   
Onyx Pharmaceuticals, Inc.
     
(b)
 
Address of Issuer's Principal Executive Offices:
   
2100 Powell Street
Emeryville, California 94608
     
Item 2.
   
(a)
 
Name of Person Filing:
   
D. E. Shaw Valence Portfolios, L.L.C.
D. E. Shaw & Co., L.P.
David E. Shaw
     
(b)
 
Address of Principal Business Office or, if none, Residence:
   
The business address for each reporting person is:
120 W. 45th Street, Tower 45, 39th Floor
New York, NY 10036
     
(c)
 
Citizenship:
   
D. E. Shaw Valence Portfolios, L.L.C. is a limited liability company organized under the laws of the state of Delaware.
D. E. Shaw & Co., L.P. is a limited partnership organized under the laws of the state of Delaware.
David E. Shaw is a citizen of the United States of America.
     
(d)
 
Title of Class of Securities:
   
Common Stock, $0.001 par value
     
(e)
 
CUSIP Number:
   
683399109
  
Item 3.
If this statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:
 
     
Not Applicable
 

Item 4.
Ownership
 
     
As of  February 26,  2008:
 
(a) Amount beneficially owned:
 
D. E. Shaw Valence Portfolios, L.L.C.:
4,261,870 shares
This is composed of (i) 3,963,570 shares in the name of D. E. Shaw Valence Portfolios, L.L.C. and (ii) 298,300 shares that D. E. Shaw Valence Portfolios, L.L.C. has the right to acquire through the exercise of listed call options.
   
D. E. Shaw & Co., L.P.:
4,374,668 shares 
This is composed of (i) 3,963,570 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (ii) 298,300 shares that D. E. Shaw Valence Portfolios, L.L.C. has the right to acquire through the exercise of listed call options, and (iii) 112,798 shares under the management of D. E. Shaw Investment Management, L.L.C.
 
David E. Shaw:
4,374,668 shares
This is composed of (i) 3,963,570 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (ii) 298,300 shares that D. E. Shaw Valence Portfolios, L.L.C. has the right to acquire through the exercise of listed call options, and (iii) 112,798 shares under the management of D. E. Shaw Investment Management, L.L.C.
 

(b) Percent of class:
 
D. E. Shaw Valence Portfolios, L.L.C.:
7.7%
 
D. E. Shaw & Co., L.P.:
7.9%
 
David E. Shaw:
7.9%
 
(c) Number of shares to which the person has:
 
(i)      Sole power to vote or to direct the vote:
 
D. E. Shaw Valence Portfolios, L.L.C.:
-0- shares
 
D. E. Shaw & Co., L.P.:
-0- shares
 
David E. Shaw:
-0- shares
 
(ii)     Shared power to vote or to direct the vote:
 
D. E. Shaw Valence Portfolios, L.L.C.:
4,261,870 shares
 
D. E. Shaw & Co., L.P.:
4,339,468 shares
 
David E. Shaw:
4,339,468 shares
 
(iii)    Sole power to dispose or to direct the disposition of:
 
D. E. Shaw Valence Portfolios, L.L.C.:
-0- shares
 
D. E. Shaw & Co., L.P.:
-0- shares
 
David E. Shaw:
-0- shares
 
(iv)    Shared power to dispose or to direct the disposition of:
 
D. E. Shaw Valence Portfolios, L.L.C.:
4,261,870 shares
 
D. E. Shaw & Co., L.P.:
4,374,668 shares
 
David E. Shaw:
4,374,668 shares
 
David E. Shaw does not own any shares directly. By virtue of David E. Shaw’s position as President and sole shareholder of D. E. Shaw & Co., Inc., which is the general partner of D. E. Shaw & Co., L.P., which in turn is the managing member and investment adviser of D. E. Shaw Valence Portfolios, L.L.C. and the managing member of D. E. Shaw Investment Management, L.L.C., David E. Shaw may be deemed to have the shared power to vote or direct the vote of 4,339,468 shares, and the shared power to dispose or direct the disposition of, 4,374,668 shares, the 4,374,668 shares as described above constituting 7.9% of the outstanding shares and, therefore, David E. Shaw may be deemed to be the beneficial owner of such shares. David E. Shaw disclaims beneficial ownership of such 4,374,668 shares.
 
Item 5.
Ownership of Five Percent or Less of a Class
Not Applicable
 
Item 6.
Ownership of More than Five Percent on Behalf of Another Person
Not Applicable
 
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person
Not Applicable
 
Item 8.
Identification and Classification of Members of the Group
Not Applicable
 
Item 9.
Notice of Dissolution of Group
Not Applicable
 
Item 10.
Certification
By signing below, each of D. E. Shaw Valence Portfolios, L.L.C., D. E. Shaw & Co., L.P., and David E. Shaw certify that, to the best of such reporting person’s knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purposes or effect.
 

 

SIGNATURE
 
After reasonable inquiry and to the best of their knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct. A Power of Attorney, dated October 24, 2007, granted by David E. Shaw in favor of Rochelle Elias, is attached hereto.

Dated: February 29, 2008
 
 
D. E. Shaw Valence Portfolios, L.L.C.
 
By:   
D. E. Shaw & Co., L.P., as managing member
 
 
 
 
    By:  /s/ Rochelle Elias
 
 
 

Rochelle Elias
Chief Compliance Officer
 
     
  D. E. Shaw & Co., L.P.
 
 
 
 
 
 
  By:    /s/ Rochelle Elias
 
Rochelle Elias
Chief Compliance Officer
 
     
  David E. Shaw
 
 
 
 
 
 
  By:    /s/ Rochelle Elias
 
Rochelle Elias
Attorney-in-Fact for David E. Shaw
 
 

 
EX-1 2 v105465_ex1.htm
Exhibit 1

POWER OF ATTORNEY
FOR CERTAIN FILINGS
UNDER THE SECURITIES EXCHANGE ACT OF 1934

I, David E. Shaw, hereby make, constitute, and appoint each of:

Anne Dinning,

Rochelle Elias,

Julius Gaudio,

John Liftin,

Louis Salkind,

Stuart Steckler,

Maximilian Stone, and

Eric Wepsic,

acting individually, as my agent and attorney-in-fact, with full power of substitution, for the purpose of, from time to time, executing in my name and/or my capacity as President of D. E. Shaw & Co., Inc. (acting for itself or as the general partner of D. E. Shaw & Co., L. P. and general partner, managing member, or manager of other entities, any of which in turn may be acting for itself or other entities) all documents, certificates, instruments, statements, other filings, and amendments to the foregoing (collectively, “documents”) determined by such person to be necessary or appropriate to comply with ownership or control-person reporting requirements imposed by any United States or non-United States governmental or regulatory authority, including without limitation Forms 3, 4, 5, and 13F and Schedules 13D and 13G required to be filed with the Securities and Exchange Commission; and delivering, furnishing, or filing any such documents to or with the appropriate governmental or regulatory authority. Any such determination shall be conclusively evidenced by such person’s execution, delivery, furnishing, and/or filing of the applicable document.

This power of attorney shall be valid from the date hereof and replaces the power granted on February 24, 2004, which is hereby cancelled.

IN WITNESS HEREOF, I have executed this instrument as of the date set forth below.

Date: October 24, 2007

DAVID E. SHAW, as President of
D. E. Shaw & Co., Inc.
/s/ David E. Shaw
New York, New York

EX-2 3 v105465_ex2.htm

Exhibit 2

JOINT FILING AGREEMENT

In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, each of the undersigned Reporting Persons hereby agrees to the joint filing, along with all other such Reporting Persons, on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock, $0.001 par value, of Onyx Pharmaceuticals, Inc., and that this Agreement be included as an Exhibit to such joint filing. This Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.

IN WITNESS WHEREOF, each of the undersigned hereby executes this Agreement as of this 29th day of February, 2008.
 
 
D. E. Shaw Valence Portfolios, L.L.C.
 
By:   
D. E. Shaw & Co., L.P., as
managing member
 
 
 
 
    By:  /s/ Rochelle Elias
 
 
 

Rochelle Elias
Chief Compliance Officer
 
     
  D. E. Shaw & Co., L.P.
 
 
 
 
 
 
  By:    /s/ Rochelle Elias
 
Rochelle Elias
Chief Compliance Officer
 
     
  David E. Shaw
 
 
 
 
 
 
  By:    /s/ Rochelle Elias
 
Rochelle Elias
Attorney-in-Fact for David E. Shaw
 
 

 
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