-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Iu1hqllsG+wYaN+FcdY7kC+9Tk8mGSMIDS+wPmc5VQfRLjMw6ZCRhIpoaKSBsIxE kymeb6G5szT1/Mh7IUB8qQ== 0001144204-07-007669.txt : 20070214 0001144204-07-007669.hdr.sgml : 20070214 20070214121010 ACCESSION NUMBER: 0001144204-07-007669 CONFORMED SUBMISSION TYPE: SC 13G/A PUBLIC DOCUMENT COUNT: 3 FILED AS OF DATE: 20070214 DATE AS OF CHANGE: 20070214 GROUP MEMBERS: D. E. SHAW & CO., L.L.C. GROUP MEMBERS: D. E. SHAW & CO., L.P. GROUP MEMBERS: DAVID E. SHAW SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: ONYX PHARMACEUTICALS INC CENTRAL INDEX KEY: 0001012140 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 943154463 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-45955 FILM NUMBER: 07616270 BUSINESS ADDRESS: STREET 1: 2100 POWELL STREET CITY: EMERYVILLE STATE: CA ZIP: 94608 BUSINESS PHONE: 5105976500 MAIL ADDRESS: STREET 1: 2100 POWELL STREET CITY: EMERYVILLE STATE: CA ZIP: 94608 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: D. E. Shaw Meniscus Portfolios, L.L.C. CENTRAL INDEX KEY: 0001324348 IRS NUMBER: 510481096 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G/A BUSINESS ADDRESS: STREET 1: 39TH FLOOR, TOWER 45 STREET 2: 120 WEST FORTY-FIFTH STREET CITY: NEW YORK STATE: NY ZIP: 10036 BUSINESS PHONE: 212-478-0000 MAIL ADDRESS: STREET 1: 39TH FLOOR, TOWER 45 STREET 2: 120 WEST FORTY-FIFTH STREET CITY: NEW YORK STATE: NY ZIP: 10036 FORMER COMPANY: FORMER CONFORMED NAME: D.E. Shaw Meniscus Portfolios, L.L.C. DATE OF NAME CHANGE: 20050420 SC 13G/A 1 v064575_sc13g-a.htm
 
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934 
(Amendment No. 2)

Onyx Pharmaceuticals, Inc.
(Name of Issuer)
 
Common Stock, $0.001 par value
(Title of Class of Securities)
 
683399109
(CUSIP Number)
 
December 31, 2006
(Date of Event Which Requires Filing of this Statement)

Check the following box to designate the rule pursuant to which the Schedule is filed:

o
Rule 13d-1(b)
x
Rule 13d-1(c)
o
Rule 13d-1(d)
 
*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
 


CUSIP No. 683399109
 
 
 
1.
Names of Reporting Persons. I.R.S. Identification Nos. of above persons (entities only)
D. E. Shaw Meniscus Portfolios, L.L.C.
51-0481096
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
   
(a)
o
 
   
(b)
o
 
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
Delaware
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
 
 
-0-
 
           
     
6.
Shared Voting Power
3,308,281
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
3,308,281
 
           
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
3,308,281
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
 
 
11.
Percent of Class Represented by Amount in Row (9)
7.2%
 
       
 
12.
Type of Reporting Person (See Instructions)
OO
 


 
CUSIP No. 683399109
 
 
1.
Names of Reporting Persons. I.R.S. Identification Nos. of above persons (entities only)
D. E. Shaw & Co., L.L.C.
13-3799946
     
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
   
(a)
o
   
(b)
o
       
 
3.
SEC Use Only
     
 
4.
Citizenship or Place of Organization
Delaware
     
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
 
 
-0-
     
     
6.
Shared Voting Power
3,308,281
         
     
7.
Sole Dispositive Power
-0-
         
     
8.
Shared Dispositive Power
3,308,281
         
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
3,308,281
     
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
     
 
11.
Percent of Class Represented by Amount in Row (9)
7.2%
     
 
12.
Type of Reporting Person (See Instructions)
OO
 


CUSIP No. 683399109
 
 
 
1.
Names of Reporting Persons. I.R.S. Identification Nos. of above persons (entities only)
D. E. Shaw & Co., L.P.
13-3695715
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
   
(a)
o
 
   
(b)
o
 
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
Delaware
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
 
 
-0-
 
       
     
6.
Shared Voting Power
3,759,503
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
3,759,503
 
           
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
3,759,503
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
 
 
11.
Percent of Class Represented by Amount in Row (9)
8.2%
 
       
 
12.
Type of Reporting Person (See Instructions)
IA, PN
 
 

 
CUSIP No. 683399109
 
   
 
1.
Names of Reporting Persons. I.R.S. Identification Nos. of above persons (entities only)
David E. Shaw
 
       
 
2.
Check the Appropriate Box if a Member of a Group (See Instructions)
 
       
   
(a)
o
 
   
(b)
o
 
         
 
3.
SEC Use Only
 
       
 
4.
Citizenship or Place of Organization
United States
 
       
Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With
5.
Sole Voting Power
 
 
-0-
 
       
     
6.
Shared Voting Power
3,759,503
 
           
     
7.
Sole Dispositive Power
-0-
 
           
     
8.
Shared Dispositive Power
3,759,503
 
           
 
9.
Aggregate Amount Beneficially Owned by Each Reporting Person
3,759,503
 
       
 
10.
Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) o
 
 
 
11.
Percent of Class Represented by Amount in Row (9)
8.2%
 
       
 
12.
Type of Reporting Person (See Instructions)
IN
 


 
Item 1.
 
 
(a)
Name of Issuer
Onyx Pharmaceuticals, Inc.
 
 
 
 
(b)
 
Address of Issuer's Principal Executive Offices
2100 Powell Street
Emeryville, California 94608
 
 
Item 2.
 
 
(a)
Name of Person Filing
D. E. Shaw Meniscus Portfolios, L.L.C.
D. E. Shaw & Co., L.L.C.
D. E. Shaw & Co., L.P.
David E. Shaw
 
 
 
(b)
Address of Principal Business Office or, if none, Residence
The business address for each reporting person is:
120 W. 45th Street, Tower 45, 39th Floor
New York, NY 10036
 
 
 
(c)
Citizenship
D. E. Shaw Meniscus Portfolios, L.L.C. is a limited liability company organized under the laws of the state of Delaware.
D. E. Shaw & Co., L.L.C. is a limited liability company organized under the laws of the state of Delaware.
D. E. Shaw & Co., L.P. is a limited partnership organized under the laws of the state of Delaware.
David E. Shaw is a citizen of the United States of America.
 
 
 
(d)
Title of Class of Securities
Common Stock, $0.001 par value
 
 
 
(e)
CUSIP Number
683399109
 
 
Item 3.
If this statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:
 
 
Not applicable
 
Item 4.
Ownership
 
  
As of December 31, 2006:
 
(a) Amount beneficially owned:
   
 
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
 
3,308,281 shares
 
D. E. Shaw & Co., L.L.C.:
 
 
3,308,281 shares
This is composed of 3,308,281 shares in the name of
D. E. Shaw Meniscus Portfolios, L.L.C.
 
D. E. Shaw & Co., L.P.:
 
 
 
 
 
3,759,503 shares 
This is composed of (i) 3,308,281 shares in the name of D. E. Shaw Meniscus Portfolios, L.L.C., (ii) 255,535 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (iii) 190,087 shares in the name of D. E. Shaw Valence, L.L.C., and (iv) 5,600 shares that D. E. Shaw Valence, L.L.C. has the right to acquire through the exercise of listed call options.
 
David E. Shaw:
 
 
3,759,503 shares
This is composed of (i) 3,308,281 shares in the name of D. E. Shaw Meniscus Portfolios, L.L.C., (ii) 255,535 shares in the name of D. E. Shaw Valence Portfolios, L.L.C., (iii) 190,087 shares in the name of D. E. Shaw Valence, L.L.C., and (iv) 5,600 shares that D. E. Shaw Valence, L.L.C. has the right to acquire through the exercise of listed call options.
 

 
(b) Percent of class:
   
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
7.2%
D. E. Shaw & Co., L.L.C.:
 
7.2%
D. E. Shaw & Co., L.P.:
 
8.2%
David E. Shaw:
 
8.2%
     
(c) Number of shares to which the person has:
(i) Sole power to vote or to direct the vote:
   
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
-0- shares
D. E. Shaw & Co., L.L.C.:
 
-0- shares
D. E. Shaw & Co., L.P.:
 
-0- shares
David E. Shaw:
 
-0- shares
     
(ii) Shared power to vote or to direct the vote:
   
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
3,308,281 shares
D. E. Shaw & Co., L.L.C.:
 
3,308,281 shares
D. E. Shaw & Co., L.P.:
 
3,759,503 shares
David E. Shaw:
 
3,759,503 shares
     
(iii) Sole power to dispose or to direct the disposition of:
   
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
-0- shares
D. E. Shaw & Co., L.L.C.:
 
-0- shares
D. E. Shaw & Co., L.P.:
 
-0- shares
David E. Shaw:
 
-0- shares
     
(iv) Shared power to dispose or to direct the disposition of:
   
D. E. Shaw Meniscus Portfolios, L.L.C.:
 
3,308,281 shares
D. E. Shaw & Co., L.L.C.:
 
3,308,281 shares
D. E. Shaw & Co., L.P.:
 
3,759,503 shares
David E. Shaw:
 
3,759,503 shares
 
David E. Shaw does not own any shares directly. By virtue of David E. Shaw’s position as President and sole shareholder of D. E. Shaw & Co., Inc., which is the general partner of D. E. Shaw & Co., L.P., which in turn is the investment adviser of D. E. Shaw Meniscus Portfolios, L.L.C., the managing member and investment adviser of D. E. Shaw Valence Portfolios, L.L.C, and the managing member of D. E. Shaw Valence, L.L.C., and by virtue of David E. Shaw’s position as President and sole shareholder of D. E. Shaw & Co. II, Inc., which is the managing member of D. E. Shaw & Co., L.L.C., which in turn is the managing member of D. E. Shaw Meniscus Portfolios, L.L.C., David E. Shaw may be deemed to have the shared power to vote or direct the vote of, and the shared power to dispose or direct the disposition of, the 3,759,503 shares as described above constituting 8.2% of the outstanding shares and, therefore, David E. Shaw may be deemed to be the beneficial owner of such shares. David E. Shaw disclaims beneficial ownership of such 3,759,503 shares.
 
Item 5.
Ownership of Five Percent or Less of a Class
 
  
Not Applicable
 
Item 6.
Ownership of More than Five Percent on Behalf of Another Person.
 
 
Not Applicable
 
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.
 
 
Not Applicable
 
Item 8.
Identification and Classification of Members of the Group
 
 
Not Applicable
 
Item 9.
Notice of Dissolution of Group
 
 
Not Applicable
 
Item 10.
Certification
 
 
By signing below, each of D. E. Shaw Meniscus Portfolios, L.L.C., D. E. Shaw & Co., L.L.C., D. E. Shaw & Co., L.P., and David E. Shaw certify that, to the best of such reporting person’s knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purposes or effect.



SIGNATURE

After reasonable inquiry and to the best of their knowledge and belief, the undersigned certify that the information set forth in this statement is true, complete and correct. Powers of Attorney, dated February 24, 2004, granted by David E. Shaw in favor of Anne Dinning, are attached hereto.

Dated: February 14, 2007
     
 
D. E. Shaw Meniscus Portfolios, L.L.C.
By:  D. E. Shaw & Co., L.L.C., as
managing member
 
 
 
 
 
 
By:  /s/ Anne Dinning

Anne Dinning
Managing Director
 
 

     
 
D. E. Shaw & Co., L.L.C.
 
 
 
 
 
 
By:   /s/ Anne Dinning
 
Anne Dinning
Managing Director
 
     
 
D. E. Shaw & Co., L.P.
 
 
 
 
 
 
By:   /s/ Anne Dinning
 
Anne Dinning
Managing Director

     
 
David E. Shaw
 
 
 
 
 
 
By:   /s/ Anne Dinning
 
Anne Dinning
Attorney-in-Fact for David E. Shaw
 

 
EX-1 2 v064575_ex1.htm
 
Exhibit 1

POWER OF ATTORNEY
FOR CERTAIN FILINGS
UNDER THE SECURITIES EXCHANGE ACT OF 1934
 
I, David E. Shaw, hereby make, constitute and appoint each of:
 
Anne Dinning,

Julius Gaudio,

Lou Salkind,

Stuart Steckler, and

Eric Wepsic,

acting individually, as my agent and attorney-in-fact, with full power of substitution, for the purpose of, from time to time, executing in my name and/or my capacity as President of D. E. Shaw & Co., Inc. (acting for itself or as the general partner of D. E. Shaw & Co., L. P. and general partner or managing member of other entities, any which in turn may be acting for itself or other entities) all documents, certificates, instruments, statement, other filings, and amendments to the forgoing (collectively, “documents”) determined by such person to be necessary or appropriate to comply with ownership or control-person reporting requirements imposed by any United States or non-United States governmental or regulatory authority, including without limitation Forms 3, 4, 5, 13D, 13F, and 13G required to be filed with the Securities and Exchange Commission; and delivering, furnishing or filing any such documents with the appropriate governmental or regulatory authority. Any such determination shall be conclusively evidenced by such person’s execution, delivery, furnishing, and/or filing of the applicable document.

This power of attorney shall be valid from the date hereof and replaces the power granted on February 5, 2001, which is hereby cancelled.

IN WITNESS HEREOF, I have executed this instrument as of the date set forth below.

Date: February 24, 2004

DAVID E. SHAW, as President of
D. E. Shaw & Co., Inc.
/s/David E. Shaw
New York, New York
 

 
EX-2 3 v064575_ex2.htm
 
Exhibit 2

POWER OF ATTORNEY
FOR CERTAIN FILINGS
UNDER THE SECURITIES EXCHANGE ACT OF 1934
 
I, David E. Shaw, hereby make, constitute and appoint each of:

Anne Dinning,

Julius Gaudio,

Lou Salkind,
 
Stuart Steckler, and

Eric Wepsic,

acting individually, as my agent and attorney-in-fact, with full power of substitution, for the purpose of, from time to time, executing in my name and/or my capacity as President of D. E. Shaw & Co. II, Inc. (acting for itself and as the managing member of D. E. Shaw & Co., L.L.C., which in turn may be acting for itself or as the managing member of other companies) all documents, certificates, instruments, statement, other filings and amendments to the forgoing (collectively, “documents”) determined by such person to be necessary or appropriate to comply with ownership or control-person reporting requirements imposed by any United States or non-United States governmental or regulatory authority, including without limitation Forms 3, 4, 5, 13D, 13F and 13G required to be filed with the Securities and Exchange Commission; and delivering, furnishing or filing any such documents with the appropriate governmental or regulatory authority. Any such determination shall be conclusively evidenced by such person’s execution and delivery, furnishing or filing of the applicable document.

This power of attorney shall be valid from the date hereof and replaces the power granted on February 5, 2001, which is hereby cancelled.

IN WITNESS HEREOF, I have executed this instrument as of the date set forth below.

Date: February 24, 2004

DAVID E. SHAW, as President of
D. E. Shaw & Co. II, Inc.
/s/David E. Shaw
New York, New York
 

 
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