Product Revenue (Details) (USD $)	3 Months Ended		6 Months Ended		1 Months Ended	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Mar. 31, 2013	Jun. 30, 2013	Dec. 31, 2012	Mar. 31, 2013 Kyprolis item	Jun. 30, 2013 Kyprolis	Jun. 30, 2012 Kyprolis	Jun. 30, 2013 Kyprolis	Jun. 30, 2012 Kyprolis	Jun. 30, 2013 Kyprolis Chargebacks	Jun. 30, 2013 Kyprolis Rebates and Other	Jun. 30, 2013 Kyprolis Distribution Fees and Returns
Product revenue
Product revenue, gross						$ 69,269,000		$ 134,728,000
Government rebates, chargebacks and other		5,900,000				(4,952,000)		(3,301,000)
Returns reserves and distribution fees						(3,280,000)		(6,382,000)
Product revenue, net	61,037,000		125,045,000			61,037,000	0	125,045,000	0
Deferred revenue								10,000,000
Deferred revenue	10,027,000		10,027,000	9,811,000
Revenue reserve for Kyprolis
Balance at the beginning of the period		9,940,000	9,940,000							5,708,000	1,946,000	2,286,000
Provision related to current period sales			15,570,000							8,345,000	843,000	6,382,000
Credits/ Payments			(14,391,000)							(8,675,000)	(116,000)	(5,600,000)
Other			(5,888,000)							(5,088,000)	(800,000)
Balance at the end of the period	$ 5,231,000		$ 5,231,000							$ 290,000	$ 1,873,000	$ 3,068,000
Number of product replacement claims received which met the requirements of the program					0
Reduction in Medicaid rebate and PHS chargeback (in dollars per share)			$ 0.08
Distribution fees and product returns
Accepted return period for expired product			3 months