Overview and Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2012

Overview and Summary of Significant Accounting Policies

Schedule of reserve established for Kyprolis

	Chargebacks			Rebates and Other		Distribution Fees and Returns			Total
	(In thousands)
Balance as of December 31, 2011	$	-		$	-	$	-		$	-
Provision related to current period sales		9,668			1,946		3,544			15,158
Credits/ Payments		(3,960	)		-		(1,258	)		(5,218	)
Balance as of December 31, 2012	$	5,708		$	1,946	$	2,286		$	9,940

Computation for basic and diluted net income (loss) per share

	Year Ended December 31,
	2012			2011		2010
	(In thousands, except per share amounts)
Numerator:
Net income (loss) — basic	$	(187,787	)	$	76,110	$	(84,847	)
Add: interest and issuance costs related to convertible senior notes		-			-		-
Net income (loss) — diluted	$	(187,787	)	$	76,110	$	(84,847	)
Denominator:
Weighted average common shares outstanding — basic		65,148			63,422		62,618
Dilutive effect of stock options		-			588		-
Weighted average common shares outstanding and dilutive potential common shares — diluted		65,148			64,010		62,618
Net income (loss) per share:
Basic	$	(2.88	)	$	1.20	$	(1.35	)
Diluted	$	(2.88	)	$	1.19	$	(1.35	)