X0202 4 2008-05-22 0 0001142596 NUVASIVE INC NUVA 0001011920 HUNT ROBERT J C/O NUVASIVE, INC. 4545 TOWNE CENTRE COURT SAN DIEGO CA 92121 1 0 0 0 Stock Option (Right to Buy) 39.45 2008-05-22 4 A 0 6000 0 A 2018-05-21 Common Stock 6000 6000 D This option was granted pursuant to the Issuer's 2004 Equity Incentive Plan which provides for an automatic annual grant of an option to purchase 6,000 shares of common stock to each non-employee director on the date of each annual stockholders meeting. The 2008 annual stockholders meeting occurred on May 22, 2008. This option vests and becomes exercisable in 12 equal installments on each monthly anniversary of the date of grant (May 22, 2008). /s/ Jason Hannon, Attorney-in-fact 2008-05-22