The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM COM 88579Y101 18,032 102,793 SH   DFND   101,629 0 1,164
ABBOTT LABORATORIES COM 002824100 400 3,390 SH   DFND   3,189 0 201
ABBVIE INC COM COM 00287Y109 30,761 285,165 SH   DFND   282,677 0 2,488
ACCENTURE PLC COM g1151c101 19,281 60,270 SH   DFND   59,885 0 385
ACTIVISION BLIZZARD INC COM 00507v109 11,419 147,552 SH   DFND   146,287 0 1,265
ADVANCE AUTO PARTS INC COM 00751y106 13,630 65,250 SH   DFND   64,746 0 504
AEGLEA BIOTHERAPEUTICS INC COM 00773j103 824 103,600 SH   DFND   103,100 0 500
AEGON NV - AMER REG SHS COM 007924103 233 45,710 SH   DFND   45,710 0 0
AFLAC INC COM COM 001055102 2,463 47,239 SH   DFND   46,735 0 504
AGILENT TECH INC COM 00846u101 326 2,070 SH   DFND   2,070 0 0
ALPHABET INC CAP STK CL A COM 02079k305 4,582 1,714 SH   DFND   1,714 0 0
ALPHABET INC CAP STK CL C COM 02079k107 45,388 17,029 SH   DFND   16,881 0 148
ALTRIA GROUP INC COM 02209s103 870 19,119 SH   DFND   19,119 0 0
AMAZON.COM INC COM 023135106 47,278 14,392 SH   DFND   14,290 0 102
AMER ELEC PWR INC COM COM 025537101 619 7,620 SH   DFND   7,603 0 17
AMERICAN EXPRESS CO COM COM 025816109 21,140 126,185 SH   DFND   125,428 0 757
AMGEN INC COM COM 031162100 566 2,661 SH   DFND   2,661 0 0
APPLE INC COM COM 037833100 75,345 532,475 SH   DFND   527,366 0 5,109
APPLIED MATERIALS INC COM 038222105 229 1,780 SH   DFND   1,780 0 0
AT&T INC. COM 00206r102 12,592 466,195 SH   DFND   459,175 0 7,021
AXION INTERNATIONAL HOLDINGS I COM 05462d101 0 95,714 SH   DFND   95,714 0 0
BANK OF AMERICA CORP COM 060505104 495 11,655 SH   DFND   11,655 0 0
BERKSHIRE HATHAWAY INC DEL CL COM 084670702 6,829 25,021 SH   DFND   24,851 0 170
BIOCRYST PHARMACEUTICALS COM 09058v103 719 50,000 SH   DFND   50,000 0 0
BIOSIGNIA INC COM 090998345 0 130,000 SH   DFND   130,000 0 0
BLACK STONE MINERALS LP COM 09225m101 337 28,000 SH   DFND   28,000 0 0
BLACKROCK INC COM COM 09247X101 37,816 45,091 SH   DFND   44,748 0 343
BOOKING HOLDINGS INC COM 09857l108 230 97 SH   DFND   97 0 0
BP PLC COM 055622104 662 24,239 SH   DFND   24,239 0 0
BRISTOLMYERS SQUIBB COM 110122108 604 10,206 SH   DFND   9,337 0 869
CALITHERA BIOSCIENCES, INC. COM 13089p101 291 133,700 SH   DFND   131,700 0 2,000
CAPITAL ONE FINANCIAL COM 14040h105 735 4,540 SH   DFND   4,540 0 0
CATERPILLAR INC COM 149123101 1,248 6,500 SH   DFND   6,500 0 0
CHEVRON CORPORATION COM 166764100 2,246 22,142 SH   DFND   22,092 0 50
CISCO SYS INC COM COM 17275R102 23,435 430,554 SH   DFND   428,047 0 2,507
CME GROUP INC COM COM 12572Q105 33,484 173,150 SH   DFND   171,587 0 1,563
COCA COLA COMPANY COM 191216100 17,470 332,955 SH   DFND   331,318 0 1,637
COMCAST CORP NEW CL A COM 20030n101 857 15,328 SH   DFND   15,328 0 0
COMMONWEALTH BANKSHARES INC (D COM 202736104 0 11,761 SH   DFND   11,761 0 0
COSTCO WHOLESALE COM 22160k105 910 2,025 SH   DFND   2,025 0 0
CUMMINS INC COM 231021106 7,399 32,947 SH   DFND   32,687 0 260
CURIS, INC. COM 231269200 402 51,400 SH   DFND   51,400 0 0
DANAHER CORP COM COM 235851102 27,056 88,873 SH   DFND   88,186 0 687
DISNEY WALT CO COM 254687106 21,795 128,835 SH   DFND   127,426 0 1,409
DOLLAR GENERAL CORP COM 256677105 13,228 62,354 SH   DFND   61,946 0 408
DOLLAR TREE STORES INC COM 256746108 232 2,420 SH   DFND   2,420 0 0
DOMINION RES INC VA NEW COM 25746u109 4,502 61,658 SH   DFND   60,329 0 1,329
DOW INC COM 260557103 515 8,946 SH   DFND   8,946 0 0
DRAFTKINGS CL A COM 26142r104 241 5,000 SH   DFND   5,000 0 0
DUKE ENERGY CORPORATION NEW COM 26441c204 1,808 18,527 SH   DFND   18,104 0 423
DUPONT DE NEMOURS INC. COM 26614n102 828 12,171 SH   DFND   12,171 0 0
ECOLAB INC COM COM 278865100 17,312 82,982 SH   DFND   82,216 0 766
ENBRIDGE INC COM 29250n105 514 12,904 SH   DFND   12,870 0 34
EXXON MOBIL CORP COM COM 30231G102 28,609 486,381 SH   DFND   483,154 0 3,227
FACEBOOK COM 30303m102 27,362 80,620 SH   DFND   80,062 0 558
FEDEXCORP COM 31428x106 237 1,083 SH   DFND   1,083 0 0
FIBROGEN INC COM 31572q808 204 20,000 SH   DFND   20,000 0 0
FIRST HORIZON NATIONAL CORP COM 320517105 259 15,883 SH   DFND   15,883 0 0
FORTUNE BRANDS HOMES & SEC INC COM 34964c106 584 6,533 SH   DFND   6,533 0 0
G1 THERAPEUTICS INC COM 3621lq109 282 21,000 SH   DFND   21,000 0 0
GENERAL DYNAMICS CRP COM 369550108 1,150 5,865 SH   DFND   5,865 0 0
GILEAD SCIENCES INC COM COM 375558103 605 8,662 SH   DFND   8,662 0 0
GOLDMAN SACHS BDC INC COM 38147u107 728 39,687 SH   DFND   39,687 0 0
GOLDMAN SACHS GROUP INC COM 38141g104 529 1,400 SH   DFND   1,400 0 0
HOME DEPOT INC COM COM 437076102 11,786 35,904 SH   DFND   35,635 0 269
HONEYWELL INTERNATIONAL INC CO COM 438516106 12,859 60,577 SH   DFND   60,192 0 385
IDEX CORPORATION COM 45167r104 4,993 24,125 SH   DFND   24,125 0 0
IDEXX LABORATORIES COM 45168d104 14,385 23,131 SH   DFND   22,932 0 199
ILLINOIS TOOL WORKS COM 452308109 875 4,235 SH   DFND   4,235 0 0
INFLARX NV COM n44821101 195 75,100 SH   DFND   75,100 0 0
INTEL CORP COM 458140100 761 14,275 SH   DFND   14,275 0 0
INTL BUSINESS MACHINES COM 459200101 1,189 8,560 SH   DFND   7,813 0 747
INTRA CELLULAR THERAPIES INC COM 46116x101 1,220 32,738 SH   DFND   32,588 0 150
INVESTORS TITLE COM 461804106 228 1,250 SH   DFND   1,250 0 0
ISHARES COMEX GOLD TR COM 464285204 203 6,090 SH   DFND   6,090 0 0
ISHARES TR DOW JONES SEL DIVID COM 464287168 1,836 16,000 SH   DFND   16,000 0 0
JOHNSON & JOHNSON COM 478160104 13,037 80,722 SH   DFND   80,025 0 698
JPMORGAN CHASE & CO COM 46625h100 37,499 229,083 SH   DFND   227,479 0 1,604
KIMBERLY CLARK CORP COM 494368103 234 1,770 SH   DFND   1,770 0 0
KINDER MORGAN INC COM 49456b101 764 45,660 SH   DFND   45,660 0 0
KKR & CO INC COM 48251w104 1,058 17,375 SH   DFND   17,375 0 0
KONINKLIJKE PHILIPS ELECTR NV COM 500472303 217 4,875 SH   DFND   4,875 0 0
KROGERCO COM 501044101 359 8,875 SH   DFND   8,875 0 0
LABORATORY CRP OF AMER HLDGS COM 50540r409 14,907 52,967 SH   DFND   52,543 0 424
LAM RESEARCH CORP COM 512807108 211 370 SH   DFND   370 0 0
LAUDER ESTEE COS INC CL A COM 518439104 16,009 53,375 SH   DFND   52,942 0 433
LINCOLN NATIONAL CORP COM 534187109 211 3,067 SH   DFND   3,067 0 0
LINDE PLC COM COM g5494j103 20,035 68,289 SH   DFND   67,888 0 401
LOWE'S COS COM 548661107 430 2,120 SH   DFND   2,120 0 0
MACQUARIE GROUP LTD COM 032870945 223 1,700 SH   DFND   1,700 0 0
MARRIOTT INTL NEW COM 571903202 12,448 84,060 SH   DFND   83,302 0 758
MARTIN MARIETTA MATERIALS INC COM 573284106 465 1,360 SH   DFND   1,360 0 0
MASCO CORP COM 574599106 322 5,796 SH   DFND   5,796 0 0
MC DONALDS CORP COM 580135101 14,895 61,775 SH   DFND   61,108 0 667
MEDTRONIC, PLC COM g5960l103 425 3,390 SH   DFND   3,390 0 0
MERCK & CO INC NEW COM 58933y105 1,026 13,661 SH   DFND   13,661 0 0
MICRONTECHNOLOGY COM 595112103 242 3,406 SH   DFND   3,406 0 0
MICROSOFT CORP COM 594918104 66,216 234,876 SH   DFND   233,209 0 1,667
MONDELEZ INTL INC COM COM 609207105 12,310 211,586 SH   DFND   209,899 0 1,687
NEKTAR THERAPEUTICS COM 640268108 557 31,000 SH   DFND   31,000 0 0
NEXTERA ENERGY INC COM 65339f101 1,234 15,712 SH   DFND   15,310 0 402
NIKE INC CL B COM 654106103 19,915 137,124 SH   DFND   136,176 0 948
NORFOLK SOUTHERN CORP COM 655844108 3,346 13,987 SH   DFND   13,987 0 0
NORTHROP GRUMMAN CORP COM 666807102 245 680 SH   DFND   680 0 0
NOVELION THERAPEUT ESCROW COM 670esc029 0 26,000 SH   DFND   26,000 0 0
NVIDIA CORP COM 67066g104 36,213 174,805 SH   DFND   173,551 0 1,254
NXP SEMICONDUCTORS NV COM n6596x109 9,408 48,033 SH   DFND   47,706 0 327
ORACLE CORP COM COM 68389X105 2,629 30,169 SH   DFND   29,889 0 280
PAYCHEX INC COM 704326107 12,382 110,115 SH   DFND   108,759 0 1,356
PAYPAL HOLDINGS INC COM 70450y103 42,358 162,785 SH   DFND   161,411 0 1,374
PEPSICO INCORPORATED COM 713448108 954 6,344 SH   DFND   6,344 0 0
PFIZER INC COM 717081103 4,766 110,801 SH   DFND   108,138 0 2,663
PHILIP MORRIS INTL INC COM 718172109 905 9,546 SH   DFND   9,546 0 0
PNC BK CORP COM COM 693475105 333 1,700 SH   DFND   1,700 0 0
PROCTER & GAMBLE COM 742718109 8,883 63,543 SH   DFND   62,024 0 1,519
PROQR THERAPEUTICS N.V. COM n71542109 837 100,000 SH   DFND   100,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 394 22,220 SH   DFND   22,000 0 220
QUALCOMM INC COM COM 747525103 682 5,291 SH   DFND   5,291 0 0
QUEST DIAGNOSTICS INC COM 74834L100 306 2,107 SH   DFND   2,107 0 0
RAYONIER INC COM COM 754907103 268 7,500 SH   DFND   7,500 0 0
RAYTHEON TECHNOLOGIES CORP COM COM 75513e101 2,234 25,986 SH   DFND   25,601 0 385
ROCKWELL INTERNATIONAL COM 773903109 1,073 3,650 SH   DFND   3,582 0 68
ROYAL BANK OF CANADA COM 780087102 1,234 12,409 SH   DFND   12,409 0 0
SABINE ROYALTY TRUST UBI COM 785688102 432 10,081 SH   DFND   10,081 0 0
SALESFORCE.COM INC COM 79466l302 23,123 85,257 SH   DFND   84,725 0 532
SANGAMO BIOSCIENCES INC COM 800677106 485 53,830 SH   DFND   53,000 0 830
SAVI MEDIA GROUP INC (NO VALUE COM 80517r207 0 294,999 SH   DFND   294,999 0 0
SCHWAB (CHARLES) CORP COM 808513105 1,446 19,855 SH   DFND   19,350 0 505
SCOTTS MIRACLE-GRO CO COM 810186106 370 2,528 SH   DFND   2,528 0 0
SELECT BANCORP INC NEW COM 81617l108 561 32,493 SH   DFND   32,493 0 0
SHERWIN WILLIAMS CO COM 824348106 379 1,356 SH   DFND   1,356 0 0
SONY CORP ADR NEW COM 835699307 323 2,924 SH   DFND   2,924 0 0
SOUTHERN CO COM 842587107 676 10,902 SH   DFND   10,851 0 51
SQUARE INC COM COM 852234103 232 967 SH   DFND   967 0 0
STANDARD & POOR'S DEP RCPTS COM 78462f103 6,108 14,232 SH   DFND   14,232 0 0
STRYKER CORP COM 863667101 1,154 4,376 SH   DFND   4,376 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 1,071 40,145 SH   DFND   40,000 0 145
SYSCO CORP COM 871829107 6,648 84,690 SH   DFND   84,119 0 571
TARGET CORPORATION COM 87612e106 1,158 5,064 SH   DFND   5,064 0 0
TESLA MOTORS INC COM 88160r101 10,825 13,959 SH   DFND   13,859 0 100
TEXAS INSTRUMENTS COM 882508104 9,075 47,214 SH   DFND   46,873 0 341
THERMO FISHER CORP COM COM 883556102 18,077 31,639 SH   DFND   31,397 0 242
TRUIST FINANCIAL CORP COM 89832q109 1,090 18,577 SH   DFND   18,577 0 0
TYME TECHNOLOGIES INC NEW COM 90238j103 41 40,000 SH   DFND   40,000 0 0
UB BANCORP COM COM 903450104 5,422 333,677 SH   DFND   333,677 0 0
UNILEVER PLC-SPONSORED ADR COM 904767704 287 5,292 SH   DFND   5,292 0 0
UNIONPACIFIC CORP COM 907818108 202 1,030 SH   DFND   1,030 0 0
UNITED HEALTHCARE CORP COM 91324p102 975 2,496 SH   DFND   2,496 0 0
UNITED PARCEL SERVICE - CL B COM 911312106 17,088 93,841 SH   DFND   92,901 0 940
V F CORP COM 918204108 7,979 119,113 SH   DFND   118,225 0 888
VERIZON COMMUNICATIONS COM 92343v104 5,367 99,375 SH   DFND   98,785 0 590
VIACOMCBS INC CL B COM 92556h206 13,735 347,636 SH   DFND   345,626 0 2,010
VIBE RECORDS INC NEW COM (DELI COM 925563108 0 11,000 SH   DFND   11,000 0 0
WALMART INC. COM 931142103 9,174 65,819 SH   DFND   65,202 0 617
WASTE MANAGEMENT INC DEL COM 94106l109 11,538 77,252 SH   DFND   76,694 0 558
WELLS FARGO & CO NEW COM 949746101 1,971 42,460 SH   DFND   42,460 0 0
ZOETIS INC COM 98978v103 13,627 70,191 SH   DFND   69,686 0 505
INVESCO S&P 500 EQUAL WEIGHT E ADR 46137v357 261 1,741 SH   DFND   1,741 0 0
iSHARE MSCI TAIWAN CAPPED ETF ADR 46434g772 620 10,000 SH   DFND   10,000 0 0
CALL (ITCI) INTRA CELLULAR JAN CALL 4355029mi 362 200 SH   DFND   200 0 0
CALL (NUE) NUCOR CORP COM JAN CALL 4355599ic 218 100 SH   DFND   100 0 0
FOREST LABORATORIES CONTINGENT WT 187cvr907 0 45,000 SH   DFND   45,000 0 0