The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM COM 88579Y101 22,863 118,658 SH   DFND   117,502 0 1,155
ABBOTT LABORATORIES COM 002824100 410 3,418 SH   DFND   3,217 0 201
ABBVIE INC COM COM 00287Y109 31,890 294,682 SH   DFND   292,150 0 2,531
ACCENTURE PLC COM g1151c101 17,571 63,605 SH   DFND   63,219 0 386
ACTIVISION BLIZZARD INC COM 00507v109 14,141 152,057 SH   DFND   150,603 0 1,454
ADVANCE AUTO PARTS INC COM 00751y106 10,563 57,567 SH   DFND   57,126 0 441
AEGLEA BIOTHERAPEUTICS INC COM 00773j103 821 103,600 SH   DFND   103,100 0 500
AFLAC INC COM COM 001055102 2,560 50,028 SH   DFND   49,343 0 685
AGILENT TECH INC COM 00846u101 311 2,445 SH   DFND   2,445 0 0
ALPHABET INC CAP STK CL A COM 02079k305 3,715 1,801 SH   DFND   1,801 0 0
ALPHABET INC CAP STK CL C COM 02079k107 38,683 18,700 SH   DFND   18,520 0 180
ALTRIA GROUP INC COM 02209s103 1,292 25,248 SH   DFND   25,248 0 0
AMAZON.COM INC COM 023135106 40,910 13,222 SH   DFND   13,118 0 104
AMER ELEC PWR INC COM COM 025537101 627 7,407 SH   DFND   7,390 0 17
AMERICAN EXPRESS CO COM COM 025816109 15,102 106,774 SH   DFND   106,067 0 707
AMGEN INC COM COM 031162100 672 2,700 SH   DFND   2,700 0 0
APPLE INC COM COM 037833100 65,273 534,367 SH   DFND   529,064 0 5,303
ART ADVANCED RESEARCH TECHNOLO COM 04287x103 0 10,000 SH   DFND   10,000 0 0
AT&T INC. COM 00206r102 7,788 257,299 SH   DFND   252,749 0 4,551
AXION INTERNATIONAL HOLDINGS I COM 05462d101 0 95,714 SH   DFND   95,714 0 0
BANK OF AMERICA CORP COM 060505104 479 12,371 SH   DFND   12,371 0 0
BERKSHIRE HATHAWAY INC DEL CL COM 084670702 14,378 56,281 SH   DFND   55,880 0 401
BIOSIGNIA INC COM 090998345 0 130,000 SH   DFND   130,000 0 0
BLACK STONE MINERALS LP COM 09225m101 244 28,000 SH   DFND   28,000 0 0
BLACKROCK INC COM COM 09247X101 36,493 48,402 SH   DFND   48,024 0 378
BOOKING HOLDINGS INC COM 09857l108 226 97 SH   DFND   97 0 0
BP PLC COM 055622104 242 9,944 SH   DFND   9,944 0 0
BRISTOLMYERS SQUIBB COM 110122108 793 12,557 SH   DFND   11,688 0 869
CALITHERA BIOSCIENCES, INC. COM 13089p101 335 138,580 SH   DFND   136,580 0 2,000
CAPITAL ONE FINANCIAL COM 14040h105 578 4,540 SH   DFND   4,540 0 0
CATERPILLAR INC COM 149123101 1,507 6,500 SH   DFND   6,500 0 0
CHEVRON CORPORATION COM 166764100 1,653 15,775 SH   DFND   15,675 0 100
CISCO SYS INC COM COM 17275R102 21,374 413,352 SH   DFND   410,944 0 2,408
CLOROX COMPANY COM 189054109 233 1,210 SH   DFND   1,210 0 0
CME GROUP INC COM COM 12572Q105 35,076 171,746 SH   DFND   170,122 0 1,624
COCA COLA COMPANY COM 191216100 8,016 152,073 SH   DFND   151,124 0 949
COMCAST CORP NEW CL A COM 20030n101 531 9,808 SH   DFND   9,808 0 0
COMMONWEALTH BANKSHARES INC (D COM 202736104 0 11,761 SH   DFND   11,761 0 0
COSTCO WHOLESALE COM 22160k105 714 2,025 SH   DFND   2,025 0 0
CUMMINS INC COM 231021106 7,567 29,205 SH   DFND   28,944 0 261
CURIS, INC. COM 231269200 226 20,000 SH   DFND   20,000 0 0
DANAHER CORP COM COM 235851102 22,605 100,431 SH   DFND   99,609 0 822
DISNEY WALT CO COM 254687106 18,665 101,154 SH   DFND   99,864 0 1,290
DOLLAR GENERAL CORP COM 256677105 507 2,502 SH   DFND   2,502 0 0
DOLLAR TREE STORES INC COM 256746108 273 2,385 SH   DFND   2,385 0 0
DOMINION RES INC VA NEW COM 25746u109 7,667 100,939 SH   DFND   99,306 0 1,633
DOW INC COM 260557103 572 8,946 SH   DFND   8,946 0 0
DRAFTKINGS CL A COM 26142r104 245 4,000 SH   DFND   4,000 0 0
DUKE ENERGY CORPORATION NEW COM 26441c204 1,546 16,016 SH   DFND   15,593 0 423
DUPONT DE NEMOURS INC. COM 26614n102 470 6,085 SH   DFND   6,085 0 0
EATON CORP COM g29183103 231 1,667 SH   DFND   1,667 0 0
ECOLAB INC COM COM 278865100 16,341 76,334 SH   DFND   75,551 0 783
ENBRIDGE INC COM 29250n105 474 13,012 SH   DFND   12,478 0 534
EXXON MOBIL CORP COM COM 30231G102 15,009 268,833 SH   DFND   267,040 0 1,793
FACEBOOK COM 30303m102 22,325 75,798 SH   DFND   75,187 0 611
FEDEXCORP COM 31428x106 313 1,103 SH   DFND   1,103 0 0
FIBROGEN INC COM 31572q808 347 10,000 SH   DFND   10,000 0 0
G1 THERAPEUTICS INC COM 3621lq109 505 21,000 SH   DFND   21,000 0 0
GENERAL DYNAMICS CRP COM 369550108 1,066 5,870 SH   DFND   5,870 0 0
GENERAL MILLS INC COM 370334104 3,363 54,848 SH   DFND   54,356 0 492
GILEAD SCIENCES INC COM COM 375558103 728 11,264 SH   DFND   11,264 0 0
GOLDMAN SACHS BDC INC COM 38147u107 415 21,446 SH   DFND   21,446 0 0
GOLDMAN SACHS BDC INC GSBD RES COM 38099d418 3,326 172,062 SH   DFND   172,062 0 0
GOLDMAN SACHS GROUP INC COM 38141g104 441 1,350 SH   DFND   1,350 0 0
HOME DEPOT INC COM COM 437076102 10,856 35,565 SH   DFND   35,261 0 304
HONEYWELL INTERNATIONAL INC CO COM 438516106 12,446 57,335 SH   DFND   56,921 0 414
IDEX CORPORATION COM 45167r104 5,050 24,125 SH   DFND   24,125 0 0
IDEXX LABORATORIES COM 45168d104 13,701 28,000 SH   DFND   27,781 0 219
ILLINOIS TOOL WORKS COM 452308109 886 4,000 SH   DFND   4,000 0 0
INFLARX NV COM n44821101 293 75,100 SH   DFND   75,100 0 0
INTEL CORP COM 458140100 945 14,761 SH   DFND   14,761 0 0
INTL BUSINESS MACHINES COM 459200101 993 7,449 SH   DFND   6,809 0 640
INTRA CELLULAR THERAPIES INC COM 46116x101 1,791 52,788 SH   DFND   52,588 0 200
ISHARES TR DOW JONES SEL DIVID COM 464287168 1,826 16,000 SH   DFND   16,000 0 0
JOHNSON & JOHNSON COM 478160104 13,300 80,927 SH   DFND   80,202 0 725
JPMORGAN CHASE & CO COM 46625h100 35,037 230,157 SH   DFND   228,523 0 1,635
KIMBERLY CLARK CORP COM 494368103 219 1,575 SH   DFND   1,575 0 0
KINDER MORGAN INC COM 49456b101 777 46,660 SH   DFND   46,660 0 0
KKR & CO INC COM 48251w104 849 17,375 SH   DFND   17,375 0 0
KONINKLIJKE PHILIPS ELECTR NV COM 500472303 231 4,042 SH   DFND   4,042 0 0
LABORATORY CRP OF AMER HLDGS COM 50540r409 13,855 54,328 SH   DFND   53,798 0 530
LAUDER ESTEE COS INC CL A COM 518439104 17,673 60,763 SH   DFND   60,278 0 485
LINDE PLC COM COM g5494j103 19,317 68,953 SH   DFND   68,495 0 458
LOWE'S COS COM 548661107 234 1,230 SH   DFND   1,230 0 0
LULULEMON ATHLETICA INC COM 550021109 7,668 25,002 SH   DFND   24,769 0 233
MARRIOTT INTL NEW COM 571903202 10,029 67,714 SH   DFND   67,012 0 702
MARTIN MARIETTA MATERIALS INC COM 573284106 751 2,237 SH   DFND   2,237 0 0
MASCO CORP COM 574599106 347 5,796 SH   DFND   5,796 0 0
MC DONALDS CORP COM 580135101 8,911 39,757 SH   DFND   39,078 0 679
MEDTRONIC, PLC COM g5960l103 1,243 10,519 SH   DFND   10,519 0 0
MERCK & CO INC NEW COM 58933y105 1,036 13,437 SH   DFND   13,437 0 0
MICROSOFT CORP COM 594918104 59,137 250,827 SH   DFND   248,977 0 1,850
MONDELEZ INTL INC COM COM 609207105 11,968 204,474 SH   DFND   202,568 0 1,906
NEKTAR THERAPEUTICS COM 640268108 310 15,500 SH   DFND   15,500 0 0
NEXTERA ENERGY INC COM 65339f101 1,296 17,145 SH   DFND   16,743 0 402
NIKE INC CL B COM 654106103 18,175 136,766 SH   DFND   135,784 0 982
NORFOLK SOUTHERN CORP COM 655844108 3,765 14,023 SH   DFND   14,023 0 0
NORTHROP GRUMMAN CORP COM 666807102 220 680 SH   DFND   680 0 0
NOVELION THERAPEUT ESCROW COM 670esc029 0 26,000 SH   DFND   26,000 0 0
NVIDIA CORP COM 67066g104 28,331 53,062 SH   DFND   52,583 0 479
NXP SEMICONDUCTORS NV COM n6596x109 10,537 52,336 SH   DFND   51,971 0 365
ORACLE CORP COM COM 68389X105 2,845 40,546 SH   DFND   40,040 0 506
PAYCHEX INC COM 704326107 11,055 112,787 SH   DFND   111,375 0 1,412
PAYPAL HOLDINGS INC COM 70450y103 40,429 166,484 SH   DFND   164,984 0 1,500
PEPSICO INCORPORATED COM 713448108 1,000 7,068 SH   DFND   7,068 0 0
PFIZER INC COM 717081103 4,672 128,943 SH   DFND   125,346 0 3,597
PHILIP MORRIS INTL INC COM 718172109 667 7,512 SH   DFND   7,512 0 0
PNC BK CORP COM COM 693475105 298 1,700 SH   DFND   1,700 0 0
PROCTER & GAMBLE COM 742718109 8,627 63,702 SH   DFND   62,183 0 1,519
PROQR THERAPEUTICS N.V. COM n71542109 661 100,000 SH   DFND   100,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 576 22,250 SH   DFND   22,000 0 250
QUALCOMM INC COM COM 747525103 673 5,074 SH   DFND   5,074 0 0
QUEST DIAGNOSTICS INC COM 74834L100 270 2,107 SH   DFND   2,107 0 0
RAYONIER INC COM COM 754907103 242 7,500 SH   DFND   7,500 0 0
RAYTHEON TECHNOLOGIES CORP COM COM 75513e101 2,002 25,910 SH   DFND   25,590 0 320
ROCKWELL INTERNATIONAL COM 773903109 1,301 4,900 SH   DFND   4,900 0 0
ROYAL BANK OF CANADA COM 780087102 1,287 13,953 SH   DFND   13,953 0 0
SABINE ROYALTY TRUST UBI COM 785688102 306 10,081 SH   DFND   10,081 0 0
SALESFORCE.COM INC COM 79466l302 18,713 88,321 SH   DFND   87,715 0 606
SANGAMO BIOSCIENCES INC COM 800677106 134 10,710 SH   DFND   9,880 0 830
SAVI MEDIA GROUP INC (NO VALUE COM 80517r207 0 294,999 SH   DFND   294,999 0 0
SCHWAB (CHARLES) CORP COM 808513105 1,294 19,855 SH   DFND   19,350 0 505
SCOTTS MIRACLE-GRO CO COM 810186106 598 2,440 SH   DFND   2,440 0 0
SELECT BANCORP INC NEW COM 81617l108 360 32,493 SH   DFND   32,493 0 0
SHERWIN WILLIAMS CO COM 824348106 378 512 SH   DFND   512 0 0
SMITH & NEPHEW PLC SPONS ADR N COM 83175M205 210 5,528 SH   DFND   5,528 0 0
SONY CORP ADR NEW COM 835699307 289 2,722 SH   DFND   2,722 0 0
SOUTHERN CO COM 842587107 619 9,960 SH   DFND   9,909 0 51
SQUARE INC COM COM 852234103 220 967 SH   DFND   967 0 0
STANDARD & POOR'S DEP RCPTS COM 78462f103 6,119 15,439 SH   DFND   15,439 0 0
STARBUCKS CORP COM 855244109 18,461 168,945 SH   DFND   167,877 0 1,068
STRYKER CORP COM 863667101 1,066 4,376 SH   DFND   4,376 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 632 24,145 SH   DFND   24,000 0 145
SYSCO CORP COM 871829107 5,031 63,890 SH   DFND   63,387 0 503
TARGET CORPORATION COM 87612e106 974 4,915 SH   DFND   4,915 0 0
TESLA MOTORS INC COM 88160r101 280 419 SH   DFND   419 0 0
TEXAS INSTRUMENTS COM 882508104 7,966 42,152 SH   DFND   41,838 0 314
THERMO FISHER CORP COM COM 883556102 15,162 33,222 SH   DFND   32,937 0 285
TRUIST FINANCIAL CORP COM 89832q109 428 7,336 SH   DFND   7,336 0 0
TYME TECHNOLOGIES INC NEW COM 90238j103 71 40,000 SH   DFND   40,000 0 0
UB BANCORP COM COM 903450104 4,671 333,677 SH   DFND   333,677 0 0
UNILEVER PLC-SPONSORED ADR COM 904767704 276 4,938 SH   DFND   4,938 0 0
UNIONPACIFIC CORP COM 907818108 236 1,073 SH   DFND   1,073 0 0
UNITED HEALTHCARE CORP COM 91324p102 1,031 2,771 SH   DFND   2,771 0 0
UNITED PARCEL SERVICE - CL B COM 911312106 14,796 87,042 SH   DFND   86,015 0 1,026
V F CORP COM 918204108 9,416 117,814 SH   DFND   116,952 0 862
VERISK ANALYTICS COM 92345y106 9,396 53,180 SH   DFND   52,794 0 386
VERIZON COMMUNICATIONS COM 92343v104 8,840 152,013 SH   DFND   150,999 0 1,014
VIBE RECORDS INC NEW COM (DELI COM 925563108 0 11,000 SH   DFND   11,000 0 0
VISA INC CL A COM 92826c839 3,425 16,178 SH   DFND   16,158 0 20
WALMART INC. COM 931142103 8,597 63,290 SH   DFND   62,623 0 667
WASTE MANAGEMENT INC DEL COM 94106l109 10,553 81,795 SH   DFND   81,200 0 595
WELLS FARGO & CO NEW COM 949746101 785 20,097 SH   DFND   20,097 0 0
ZOETIS INC COM 98978v103 11,515 73,119 SH   DFND   72,533 0 586
INVESCO S&P 500 EQUAL WEIGHT E ADR 46137v357 255 1,800 SH   DFND   1,800 0 0
iSHARE MSCI TAIWAN CAPPED ETF ADR 46434g772 600 10,000 SH   DFND   10,000 0 0
FOREST LABORATORIES CONTINGENT WT 187cvr907 0 45,000 SH   DFND   45,000 0 0