Note 3 - Procurement Contracts and Research Agreements (Details Textual) $ in Thousands				3 Months Ended		12 Months Ended
	Sep. 07, 2021 USD ($)	Jan. 13, 2021 USD ($)	Apr. 03, 2020 USD ($)	Sep. 30, 2021 USD ($)	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	May 31, 2020 USD ($)	Jul. 31, 2019 USD ($)	Sep. 10, 2018 USD ($)	May 13, 2011
Contract with Customer, Liability, Revenue Recognized						$ 100	$ 100
The 19C BARDA Contract [Member]
Number of Courses to Be Delivered										1,488,000
Number of Courses Stored As Vendor Managed Inventory										212,000
Government Contract, Value of Award						602,500
Government Contract, Base Period, Value of Award for Delivery and Support Activities						$ 51,700				$ 51,700
Base Period of Performance (Year)						5 years
Government Contract, Value, Payments Remaining Related to Exercised Options						$ 239,700
Government Contract, Value, Payments Currently Specified as Unexercised Options						$ 311,100
Government Contract, Option Exercised, Value of Consideration	$ 112,600
Base Period of Performance, Exercise of Options, Term (Year)						10 years
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Delivery of Courses										$ 11,100
Government Contract, Base Period, Number of Deliveries										35,700
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Manufacture of Courses										$ 8,000
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Advanced Development										32,000
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Supportive Procurement Activities										$ 600
Proceeds from Delivery of Courses						$ 11,100
Number of Courses Delivered						35,700
Proceeds from Other Base Period Activities						$ 13,800
Government Contract, Value of Unexercised Options, Supportive Procurement Activities						5,600
The 19C BARDA Contract [Member] | Transferred over Time [Member]
Contract with Customer, Liability, Revenue Recognized						4,800	7,500
The 19C BARDA Contract [Member] | Transferred at Point in Time [Member]
Proceeds from Delivery of Courses						112,500
Contract with Customer, Liability, Revenue Recognized							$ 112,600
The 19C BARDA Contract [Member] | IV TPOXX [Member]
Government Contract, Base Period, Number of Courses Manufactured										20,000
Government Contract, Value, Payments Related to Exercised Options, Funding of Post-Marketing Activities						3,600
Government Contract, Value, Payments Related to Unexercised Options, Delivery of Courses						$ 225,100
Number of Manufacturing Steps						2
The 19C BARDA Contract [Member] | IV BDS [Member]
Government Contract, Base Period, Value of Award for Delivery and Support Activities, Manufacture of Courses										$ 3,200
Proceeds from the Manufacture of Courses						$ 3,200
Contract with Customer, Liability, Total						3,200
Government Contract, Value, Payments Currently Specified as Unexercised Options, Manufacture of Courses						$ 30,700
Government Contract, Number of Options for Manufacture of Product						3
Government Contract, Courses Manufactured Upon Exercise of Options						64,000
The 19C BARDA Contract [Member] | Oral TPOXX [Member]
Number of Courses to Be Delivered							726,140
Proceeds from Delivery of Courses						$ 112,500
Government Contract, Value, Payments Related to Exercised Options, Procurement of Raw Materials						225,100	$ 11,200
Government Contract, Value, Payments Related to Exercised Options, Delivery of Courses							213,900
Government Contract, Value, Payments Related to Exercised Options, Funding of Post-Marketing Activities						7,300	14,600
Government Contract, Value, Delivered and Invoiced						79,700
The 19C BARDA Contract [Member] | IV FDP [Member]
Government Contract, Value, Payments Currently Specified as Unexercised Options, Manufacture of Courses						$ 76,800
Government Contract, Number of Options for Manufacture of Product						3
Government Contract, Courses Manufactured Upon Exercise of Options						64,000
The 2011 BARDA Contract [Member]
Number of Courses to Be Delivered											1,700,000
Government Contract, Value of Award						$ 508,400
Proceeds from the Manufacture and Delivery of Courses						459,800
Proceeds from Reimbursements in Connection with Development and Supportive Activities						45,900
Amount Eligible to be Received for Reimbursements of Development and Supportive Activities						2,700
IC BARDA [Member]
Contract with Customer, Liability, Revenue Recognized						200	200
IC BARDA [Member] | Transferred at Point in Time [Member]
Contract with Customer, Liability, Revenue Recognized						0	400
Meridian Contract [Member] | Oral TPOXX [Member]
Government Contract, Value of Award		$ 33,000
Contract with Customer, Liability, Revenue Recognized						10,000
Government Contract, Term (Year)		5 years
Government Contract, Increased Value of Award						38,000
Government Contract, Firm Commitment not Subject to Option Exercise		$ 23,000
Canadian Contract [Member] | Meridian Medical Technologies [Member]
Contract with Customer, Liability, Revenue Recognized						12,700
Government Contract, Term (Year)			4 years
Other Commitment, Total			$ 14,000
Canadian Contract [Member] | Meridian Medical Technologies [Member] | Purchases from Q2 of 2020 [Member]
Contract with Customer, Liability, Revenue Recognized					$ 2,000
Canadian Contract [Member] | Meridian Medical Technologies [Member] | Purchases from Q3 of 2021 [Member]
Contract with Customer, Liability, Revenue Recognized				$ 2,000
Canadian Contract [Member] | Transferred at Point in Time [Member]
Contract with Customer, Liability, Revenue Recognized							2,300
The IV Formulation R & D Contract with BARDA [Member]
Contract with Customer, Liability, Revenue Recognized						800	1,400
Government Contract, Future Aggregate Research and Development Funding						500
The PEP Label Expansion R & D Contract with the Department of Defense [Member]
Government Contract, Value of Award								$ 26,000	$ 19,500
Contract with Customer, Liability, Revenue Recognized							$ 300
Government Contract, Future Aggregate Research and Development Funding						23,300
Government Contract, Initial Award									$ 12,400
The PEP Label Expansion R & D Contract with the Department of Defense [Member] | Transferred over Time [Member]
Contract with Customer, Liability, Revenue Recognized						$ 2,500