Financial Information by Quarter (Unaudited) (Details) (USD $)	3 Months Ended									6 Months Ended		9 Months Ended		12 Months Ended
	Mar. 31, 2013	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2011	Sep. 30, 2011	Jun. 30, 2011	Mar. 31, 2011	Jun. 30, 2012	Jun. 30, 2011	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Research and Development Revenue	$ 1,465,752	$ 2,514,000	$ 2,289,820	$ 2,701,164	$ 1,466,000	$ 4,960,000	$ 3,577,948	$ 2,491,056	$ 1,696,721	$ 4,166,916	$ 4,187,777	$ 6,456,736	$ 7,765,725	$ 8,970,835	$ 12,725,792	$ 19,215,837
Selling, General and Administrative Expense		2,583,000	3,139,000	3,475,000	2,214,000	6,363,000	3,969,000	9,351,000	4,250,000					11,410,131	23,931,713	8,130,669
Research and Development Expense		4,396,000	4,170,000	5,183,000	4,465,000	5,795,000	5,170,000	3,835,000	3,566,000					18,213,036	18,367,348	22,658,959
Patent preparation fees		794,000	377,000	376,000	336,000	571,000	482,000	413,000	342,000					1,883,405	1,808,168	1,148,597
Operating loss	(5,548,961)	(5,259,000)	(5,395,799)	(6,332,363)	(5,549,000)	(7,769,000)	(6,043,144)	(11,107,919)	(6,461,440)	(11,881,324)	(17,569,358)	(17,277,125)	(23,612,503)	(22,535,737)	(31,381,437)	(12,722,388)
Net income (loss)	(4,615,609)	(2,618,000)	(3,058,734)	(3,766,838)	(4,616,000)	(5,061,000)	8,326,309	27,345,796	(1,512,000)	(8,382,447)	25,834,234	(11,441,183)	34,160,542	(14,059,539)	29,099,579	(50,348,301)
Earnings (loss) per share: diluted		$ (0.04)	$ (0.06)	$ (0.07)	$ (0.09)	$ (0.11)	$ 0.11	$ 0.40	$ (0.03)		$ 0.28		$ 0.20	$ (0.27)	$ 0.09	$ (1.12)
Earning (loss) per share: basic		$ (0.04)	$ (0.06)	$ (0.07)	$ (0.09)	$ (0.11)	$ 0.16	$ 0.54	$ (0.03)		$ 0.51		$ 0.67	$ (0.27)	$ 0.57	$ (1.12)
Scenario, Previously Reported [Member]
Research and Development Revenue	1,465,752		2,289,820	2,701,164		4,960,000	3,577,948	2,491,056	1,696,721	4,166,916	4,187,777	6,456,736	7,765,725	8,970,835	12,725,792	19,215,837
Selling, General and Administrative Expense						6,362,000								11,410,131	23,931,713	8,130,669
Research and Development Expense						5,796,000								18,213,036	18,367,348	22,658,959
Patent preparation fees						571,000								1,883,405	1,808,168	1,148,597
Operating loss	(5,548,961)		(5,395,799)	(6,332,363)		(7,769,000)	(6,043,144)	(11,107,919)	(6,461,440)	(11,881,324)	(17,569,358)	(17,277,125)	(23,612,503)	(22,535,737)	(31,381,437)	(12,722,388)
Net income (loss)	$ (4,052,893)		$ (2,940,391)	$ (4,346,557)		$ (5,757,000)	$ 210,514	$ 23,841,926		$ (8,399,450)	$ 19,140,652	$ (11,339,843)	$ 19,351,165	$ (14,528,153)	$ 13,594,176	$ (28,195,339)
Earnings (loss) per share: diluted						$ (0.11)	$ 0.00	$ 0.40			$ 0.28		$ 0.20	$ (0.28)	$ 0.09	$ (0.62)
Earning (loss) per share: basic						$ (0.11)	$ 0.00	$ 0.47			$ 0.38		$ 0.38	$ (0.28)	$ 0.27	$ (0.62)