Financial Information By Quarter (Unaudited)

As previously discussed in Note 3, the Company concluded that the previously issued quarterly periods in the year ended December 31, 2011 included in the Company’s quarterly reports on Forms 10-Q are no longer appropriate to rely upon and have been restated and that the previously issued quarterly periods in the year ended December 31, 2012 have been revised.



	Three Months Ended
2012	March 31 (Revised)			June 30 (Revised)			September 30 (Revised)			December 31 (Revised)
	(in thousands, except for per share data)
Revenues	$	1,466		$	2,701		$	2,290		$	2,514
Selling, general and administrative	2,214			3,475			3,139			2,583
Research and development	4,465			5,183			4,170			4,396
Patent preparation fees	336			376			377			794
Operating loss	(5,549		)	(6,332		)	(5,396		)	(5,259		)
Net income (loss)	(4,616		)	(3,767		)	(3,059		)	(2,618		)
Earnings (loss) per share: basic	$	(0.09	)	$	(0.07	)	$	(0.06	)	$	(0.04	)
Earnings (loss) per share: diluted	$	(0.09	)	$	(0.07	)	$	(0.06	)	$	(0.04	)



	Three Months Ended
2011	March 31			June 30			September 30			December 31
	(Restated)			(Restated)			(Restated)			As Originally Reported			Restated
	(in thousands, except for per share data)
Revenues	$	1,697		$	2,491		$	3,578		$	4,960		$	4,960
Selling, general and administrative	4,250			9,351			3,969			6,362			6,363
Research and development	3,566			3,835			5,170			5,796			5,795
Patent preparation fees	342			413			482			571			571
Operating loss	(6,461		)	(11,108		)	(6,043		)	(7,769		)	(7,769		)
Net income (loss)	(1,512		)	27,346			8,326			(5,757		)	(5,061		)
Earnings (loss) per share: basic	$	(0.03	)	$	0.54		$	0.16		$	(0.11	)	$	(0.11	)
Earnings (loss) per share: diluted	$	(0.03	)	$	0.40		$	0.11		$	(0.11	)	$	(0.11	)

The effects of the revision and restatement on the unaudited consolidated balance sheets are summarized in the following tables:



	September 30, 2012						September 30, 2011
	As Originally Reported		Adjustments		Revised		As Originally Reported		Adjustments		Restated
Total current assets	42,540,233				42,540,233		14,538,719				14,538,719
Total noncurrent assets	49,511,759				49,511,759		36,245,375				36,245,375
Total assets	92,051,992				92,051,992		50,784,094				50,784,094
Common stock warrants, current	—		235,046		235,046		—		233,499		233,499
Common stock warrants, non-current	749,771		1,038,911		1,788,682		1,024,987		1,377,733		2,402,720
Other liabilities	59,562,651		—		59,562,651		3,779,449		—		3,779,449
Total liabilities	60,312,422		1,273,957		61,586,379		4,804,436		1,611,232		6,415,668
Common stock	5,164				5,164		5,142				5,142
Additional paid-in capital	151,944,558		15,248,071		167,192,629		149,087,836		15,505,481		164,593,317
Accumulated deficit	(120,210,152	)	(16,522,028	)	(136,732,180	)	(103,113,320	)	(17,116,713	)	(120,230,033	)
Total stockholders' equity	31,739,570		(1,273,957	)	30,465,613		45,979,658		(1,611,232	)	44,368,426
Total liabilities and stockholders' equity	92,051,992		—		92,051,992		50,784,094		—		50,784,094



	June 30, 2012						June 30, 2011
	As Originally Reported		Adjustments		Revised		As Originally Reported		Adjustments		Restated
Total current assets	46,578,955				46,578,955		17,240,832				17,240,832
Total noncurrent assets	46,062,035				46,062,035		34,727,750				34,727,750
Total assets	92,640,990				92,640,990		51,968,582				51,968,582
Common stock warrants, current	—		100,637		100,637		—		1,686,760		1,686,760
Common stock warrants, non-current	734,739		1,054,977		1,789,716		5,751,035		8,040,268		13,791,303
Other liabilities	57,661,062		—		57,661,062		3,268,952		—		3,268,952
Total liabilities	58,395,801		1,155,614		59,551,415		9,019,987		9,727,028		18,747,015
Common stock	5,164				5,164		5,131				5,131
Additional paid-in capital	151,509,784		15,248,071		166,757,855		146,267,297		15,505,481		161,772,778
Accumulated deficit	(117,269,759	)	(16,403,685	)	(133,673,444	)	(103,323,833	)	(25,232,509	)	(128,556,342	)
Total stockholders' equity	34,245,189		(1,155,614	)	33,089,575		42,948,595		(9,727,028	)	33,221,567
Total liablities and stockholders' equity	92,640,990		—		92,640,990		51,968,582		—		51,968,582



	March 31, 2012						March 31, 2011
	As Originally Reported		Adjustments		Revised		As Originally Reported		Adjustments		Restated
Total current assets	46,636,330				46,636,330		20,423,847				20,423,847
Total noncurrent assets	42,391,291				42,391,291		2,203,499				2,203,499
Total assets	89,027,621				89,027,621		22,627,346				22,627,346
Common stock warrants, current	—		157,014		157,014		—		—		—
Common stock warrants, non-current	1,059,751		1,320,909		2,380,660		7,790,886		13,487,647		21,278,533
Other liabilities	50,017,901		—		50,017,901		3,474,238		—		3,474,238
Total liabilities	51,077,652		1,477,923		52,555,575		11,265,124		13,487,647		24,752,771
Common stock	5,164				5,164		5,038				5,038
Additional paid-in capital	150,868,007		15,505,481		166,373,488		138,522,944		15,248,732		153,771,676
Accumulated deficit	(112,923,202	)	(16,983,404	)	(129,906,606	)	(127,165,760	)	(28,736,379	)	(155,902,139	)
Total stockholders' equity	37,949,969		(1,477,923	)	36,472,046		11,362,222		(13,487,647	)	(2,125,425	)
Total liablities and stockholders' equity	89,027,621		—		89,027,621		22,627,346		—		22,627,346

The effects of the revision and restatement on the unaudited consolidated statements of operations and comprehensive income/loss are summarized in the following tables:



	Three months ended September 30, 2012									Nine months ended September 30, 2012
	As Originally Reported			Adjustments			Revised			As Originally Reported			Adjustments			Revised
Revenues	$	2,289,820					$	2,289,820		$	6,456,736					$	6,456,736
Total operating expenses	7,685,619						7,685,619			23,733,861						23,733,861
Operating loss	(5,395,799		)				(5,395,799		)	(17,277,125		)				(17,277,125		)
Decrease (increase) in fair value of common stock warrants	(15,032		)	$	(118,343	)	(133,375		)	(126,833		)	$	(101,340	)	(228,173		)
Interest expense and other income (loss)	94						94			330						330
Benefit from (provision for) income taxes	2,470,346						2,470,346			6,063,785						6,063,785
Net income (loss)	$	(2,940,391	)	$	(118,343	)	$	(3,058,734	)	$	(11,339,843	)	$	(101,340	)	$	(11,441,183	)
Diluted earnings (loss) per share	$	(0.06	)	$	—		$	(0.06	)	$	(0.22	)	$	—		$	(0.22	)
Weighted average shares outstanding, diluted	51,639,811						51,639,811			51,638,648						51,638,648



	Three months ended June 30, 2012								Six months ended June 30, 2012
	As Originally Reported			Adjustments		Revised			As Originally Reported			Adjustments		Revised
Revenues	$	2,701,164				$	2,701,164		$	4,166,916				$	4,166,916
Total operating expenses	9,033,527					9,033,527			16,048,240					16,048,240
Operating loss	(6,332,363		)			(6,332,363		)	(11,881,324		)			(11,881,324		)
Decrease (increase) in fair value of common stock warrants	325,012			$	579,719	904,731			(111,801		)	$	17,003	(94,798		)
Interest expense and other income (loss)	74					74			236					236
Benefit from (provision for) income taxes	1,660,720					1,660,720			3,593,439					3,593,439
Net income (loss)	$	(4,346,557	)	$	579,719	$	(3,766,838	)	$	(8,399,450	)	$	17,003	$	(8,382,447	)
Earnings (loss) per share: basic and diluted	$	(0.08	)	$	0.01	$	(0.07	)	$	(0.16	)	$	—	$	(0.16	)
Weighted average shares outstanding: basic and diluted	51,638,352					51,638,352			51,638,061					51,638,061



	Three months ended March 31, 2012
	As Originally Reported			Adjustments			Revised
Revenues	$	1,465,752					$	1,465,752
Total operating expenses	7,014,713						7,014,713
Operating loss	(5,548,961		)				(5,548,961		)
Decrease (increase) in fair value of common stock warrants	(436,813		)	$	(562,716	)	(999,529		)
Interest expense and other income (loss)	162						162
Benefit from (provision for) income taxes	1,932,719						1,932,719
Net income (loss)	$	(4,052,893	)	$	(562,716	)	$	(4,615,609	)
Earnings (loss) per share: basic and diluted	$	(0.08	)	$	(0.01	)	$	(0.09	)
Weighted average shares outstanding: basic and diluted	51,637,770						51,637,770



	Three months ended September 30, 2011								Nine months ended September 30, 2011
	As Originally Reported			Adjustments		Restated			As Originally Reported			Adjustments		Restated
Revenues	$	3,577,948				$	3,577,948		$	7,765,725				$	7,765,725
Total operating expenses	9,621,092					9,621,092			31,378,228					31,378,228
Operating loss	(6,043,144		)			(6,043,144		)	(23,612,503		)			(23,612,503		)
Decrease (increase) in fair value of common stock warrants	4,726,054			$	8,115,795	12,841,849			8,528,863			$	14,809,377	23,338,240
Interest expense and other income (loss)	329					329			12,429					12,429
Benefit from (provision for) income taxes	1,527,275					1,527,275			34,422,376					34,422,376
Net income (loss)	$	210,514		$	8,115,795	$	8,326,309		$	19,351,165		$	14,809,377	$	34,160,542
Basic earnings (loss) per share	$	—		$	0.16	$	0.16		$	0.38		$	0.29	$	0.67
Diluted earnings (loss) per share	$	—		$	0.11	$	0.11		$	0.20		$	—	$	0.20
Weighted average shares outstanding, basic	50,806,284					50,806,284			50,739,475					50,739,475
Weighted average shares outstanding, diluted	51,987,253					51,987,253			54,234,977					54,234,977



	Three months ended June 30, 2011								Six months ended June 30, 2011
	As Originally Reported			Adjustments		Restated			As Originally Reported			Adjustments		Restated
Revenues	$	2,491,056				$	2,491,056		$	4,187,777				$	4,187,777
Total operating expenses	13,598,975					13,598,975			21,757,135					21,757,135
Operating loss	(11,107,919		)			(11,107,919		)	(17,569,358		)			(17,569,358		)
Decrease (increase) in fair value of common stock warrants	2,039,851			$	3,503,870	5,543,721			3,802,809			$	6,693,582	10,496,391
Interest expense and other income (loss)	2,006					2,006			12,100					12,100
Benefit from (provision for) income taxes	32,907,988					32,907,988			32,895,101					32,895,101
Net income (loss)	$	23,841,926		$	3,503,870	$	27,345,796		$	19,140,652		$	6,693,582	$	25,834,234
Basic earnings (loss) per share	$	0.47		$	0.07	$	0.54		$	0.38		$	0.13	$	0.51
Diluted earnings (loss) per share	$	0.40		$	—	$	0.40		$	0.28		$	—	$	0.28
Weighted average shares outstanding, basic	50,879,599					50,879,599			50,422,014					50,422,014
Weighted average shares outstanding, diluted	54,671,403					54,671,403			54,507,838					54,507,838



	Three months ended March 31, 2011
	As Originally Reported			Adjustments		Restated
Revenues	$	1,696,721				$	1,696,721
Total operating expenses	8,158,161					8,158,161
Operating loss	(6,461,440		)			(6,461,440		)
Decrease (increase) in fair value of common stock warrants	1,762,958			$	3,189,712	4,952,670
Interest expense and other income (loss)	(2,793		)			(2,793		)
Net income (loss)	$	(4,701,275	)	$	3,189,712	$	(1,511,563	)
Earnings (loss) per share: basic and diluted	$	(0.09	)	$	0.06	$	(0.03	)
Weighted average shares outstanding: basic and diluted	49,959,345					49,959,345