X0303 4 2009-06-17 0 0001009356 SALIX PHARMACEUTICALS LTD SLXP 0001212669 DERBYSHIRE ADAM C 1700 PERIMETER PARK DRIVE MORRISVILLE NC 27560 0 1 0 0 EVP Finance/CFO Common Stock 2009-06-17 4 M 0 1000 1.1333 A 84389 D Common Stock 2009-06-17 4 S 0 300 9.85 D 84089 D Common Stock 2009-06-17 4 S 0 100 9.81 D 83989 D Common Stock 2009-06-17 4 S 0 100 9.80 D 83889 D Common Stock 2009-06-17 4 S 0 200 9.78 D 83689 D Common Stock 2009-06-17 4 S 0 200 9.77 D 83489 D Common Stock 2009-06-17 4 S 0 100 9.76 D 83389 D Common Stock 2009-06-18 4 M 0 1000 1.1333 A 84389 D Common Stock 2009-06-18 4 S 0 100 10.13 D 84289 D Common Stock 2009-06-18 4 S 0 1 10.10 D 84288 D Common Stock 2009-06-18 4 S 0 199 10.07 D 84089 D Common Stock 2009-06-18 4 S 0 200 10.06 D 83889 D Common Stock 2009-06-18 4 S 0 100 9.99 D 83789 D Common Stock 2009-06-18 4 S 0 200 9.98 D 83589 D Common Stock 2009-06-18 4 S 0 100 9.96 D 83489 D Common Stock 2009-06-18 4 S 0 100 9.88 D 83389 D Common Stock 2009-06-19 4 M 0 1000 1.1333 A 84389 D Common Stock 2009-06-19 4 S 0 100 10.27 D 84289 D Common Stock 2009-06-19 4 S 0 100 10.25 D 84189 D Common Stock 2009-06-19 4 S 0 500 10.24 D 83689 D Common Stock 2009-06-19 4 S 0 200 10.22 D 83489 D Common Stock 2009-06-19 4 S 0 100 10.21 D 83389 D Option to Buy Common Stock 17.63 2015-06-09 Common Stock 20000 20000 D Option to Buy Common Stock 18.8733 2014-06-17 Common Stock 30000 30000 D Option to Buy Common Stock 8.00 2013-05-30 Common Stock 90000 90000 D Option to Buy Common Stock 4.0666 2012-07-02 Common Stock 30000 30000 D Option to Buy Common Stock 1.1333 2009-06-17 4 M 0 1000 1.1333 D 2010-06-12 Common Stock 1000 126000 D Option to Buy Common Stock 1.1333 2009-06-18 4 M 0 1000 1.1333 D 2010-06-12 Common Stock 1000 125000 D Option to Buy Common Stock 1.1333 2009-06-19 4 M 0 1000 1.1333 D 2010-06-12 Common Stock 1000 124000 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 8, 2009. Option vests at a rate of 1/48th per month, with a vesting commencement date of July 1, 2005. Option vested at a rate of 1/48th per month, with a vesting commencement date of July 1, 2004. Option vested at a rate of 1/48th per month, with a vesting commencement date of May 1, 2003. Option vested at a rate of 1/48th per month, with a vesting commencement date of July 1, 2002. Option vested at a rate of 1/48th per month, with a vesting commencement date of June 1, 2000. Adam C. Derbyshire 2009-06-19