The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
AAC HLDGS INCCOM00030710813,649446,328SH DFND1446,32800
ABBOTT LABSCOM00282410060213,000SH DFND113,00000
ABBVIE INCCOM00287Y10989,8001,534,000SH DFND11,534,00000
ACADIA PHARMACEUTICALS INCCOM0042251081,61049,400SH DFND149,40000
ACCURAY INCNOTE 3.750% 8/0004397AB126,69424,100,000PRN DFND124,100,00000
ACHILLION PHARMACEUTICALS INCOM00448Q20127,7082,810,164SH DFND12,810,16400
ADEPTUS HEALTH INCCL A0068551009,974198,600SH DFND1198,60000
AERIE PHARMACEUTICALS INCCOM00771V10818,996606,118SH DFND1606,11800
AETERNA ZENTARIS INCCOM NEW007975303482898,574SH DFND1898,57400
AETNA INC NEWCOM00817Y10830,286284,300SH DFND1284,30000
AGILE THERAPEUTICS INCCOM00847L100973105,000SH DFND1105,00000
ALCOBRA LTDSHSM2239P1097,9561,413,208SH DFND11,413,20800
ALIMERA SCIENCES INCCOM01625910322,1474,420,580SH DFND14,420,58000
ALKERMES PLCSHSG017671051,06717,500SH DFND117,50000
ALLSCRIPTS HEALTHCARE SOLUTNNOTE 1.250% 7/001988PAD098,882100,750,000PRN DFND1100,750,00000
ALPHATEC HOLDINGS INCCOM02081G1027,2254,982,738SH DFND14,982,73800
AMPHASTAR PHARMACEUTICALS INCOM03209R1036,710448,532SH DFND1448,53200
ANTARES PHARMA INCCOM03664210632,73212,078,318SH DFND112,078,31800
ANTHEM INCCOM03675210315,40199,742SH DFND199,74200
ARENA PHARMACEUTICALS INCCOM04004710240,3329,229,379SH DFND19,229,37900
ARRAY BIOPHARMA INCCOM04269X10587,22111,834,595SH DFND111,834,59500
ARRAY BIOPHARMA INCNOTE 3.000% 6/004269XAA356,03745,000,000PRN DFND145,000,00000
ASCENDIS PHARMA A SSPONSORED ADR04351P1013,470200,000SH DFND1200,00000
AUSPEX PHARMACEUTICALS INCCOM05211J102446,1124,449,103SH DFND14,449,10300
AVALANCHE BIOTECHNOLOGIES INCOM05337G10785,8002,117,473SH DFND12,117,47300
AXOGEN INCCOM05463X10613,5483,870,824SH DFND13,870,82400
BIOTELEMETRY INCCOM0906721065,702644,300SH DFND1644,30000
BLUEBIRD BIO INCCOM09609G10076,243631,309SH DFND1631,30900
BOVIE MEDICAL CORPCOM10211F1001,673700,000SH DFND1700,00000
CARA THERAPEUTICS INCCOM1407551094,760473,588SH DFND1473,58800
CAREDX INCCOM14167L1034,458804,000SH DFND1804,00000
CAS MED SYS INCCOM PAR $0.0041247692094,2723,200,000SH DFND13,200,00000
CELGENE CORPCOM1510201044033,500SH DFND13,50000
CELLECTIS S ASPONSORED ADS15117K1035,204150,506SH DFND1150,50600
CHARLES RIV LABS INTL INCCOM15986410722,950289,450SH DFND1289,45000
CROSS CTRY HEALTHCARE INCCOM2274831044,349366,724SH DFND1366,72400
DAVITA HEALTHCARE PARTNERS ICOM23918K10859,334730,000SH DFND1730,00000
DBV TECHNOLOGIES S ASPONSORED ADR23306J1016,964298,121SH DFND1298,12100
DERMA SCIENCES INCCOM PAR $.012498275028,394991,040SH DFND1991,04000
DERMIRA INCCOM24983L1043,553231,467SH DFND1231,46700
DISCOVERY LABORATORIES INC NCOM NEW2546684034,3553,659,700SH DFND13,659,70000
DYAX CORPCOM26746E10318,9571,131,414SH DFND11,131,41400
EHEALTH INCCOM28238P10930,6223,264,588SH DFND13,264,58800
ENDOLOGIX INCCOM29266S10640,1032,349,351SH DFND12,349,35100
ENDOLOGIX INCNOTE 2.250%12/129266SAA435,20334,925,000PRN DFND134,925,00000
ESPERION THERAPEUTICS INC NECOM29664W1052322,500SH DFND12,50000
EXELIXIS INCCOM30161Q10410,2804,000,000SHPutDFND14,000,00000
EXELIXIS INCNOTE 4.250% 8/130161QAC83,7624,985,000PRN DFND14,985,00000
FLAMEL TECHNOLOGIES SASPONSORED ADR33848810973,2294,072,809SH DFND14,072,80900
FLUIDIGM CORP DELNOTE 2.750% 2/034385PAA610,63210,000,000PRN DFND110,000,00000
FOAMIX PHARMACEUTICALS LTDSHSM461351056,287679,627SH DFND1679,62700
GENESIS HEALTHCARE INCCL A COM37185X10610,1981,432,368SH DFND11,432,36800
GENOCEA BIOSCIENCES INCCOM37242710410,013844,257SH DFND1844,25700
GILEAD SCIENCES INCCOM37555810319,626200,000SHPutDFND1200,00000
GLAXOSMITHKLINE PLCSPONSORED ADR37733W10540,297873,185SH DFND1873,18500
GW PHARMACEUTICALS PLCADS36197T10333,144363,700SH DFND1363,70000
HEALTHWAYS INCNOTE 1.500% 7/0422245AB67,8166,700,000PRN DFND16,700,00000
HEARTWARE INTL INCNOTE 3.500%12/1422368AA823,22720,464,000PRN DFND120,464,00000
HMS HLDGS CORPCOM40425J10146229,900SH DFND129,90000
HORIZON PHARMA INCNOTE 5.000%11/144047TAB578,18916,014,461PRN DFND116,014,46100
HORIZON PHARMA PLCSHSG4617B105332,22612,792,689SH DFND112,792,68900
HUMANA INCCOM44485910218,924106,300SH DFND1106,30000
ILLUMINA INCCOM4523271091,1886,400SH DFND16,40000
IMMUNOMEDICS INCCOM4529071089,5982,505,972SH DFND12,505,97200
IMMUNOMEDICS INCCOM4529071081,915500,000SHCallDFND1500,00000
IMPRIVATA INCCOM45323J10314,3591,025,652SH DFND11,025,65200
IMRIS INCCOM45322N105141147,076SH DFND1147,07600
INFINITY PHARMACEUTICALS INCCOM45665G30355,4753,968,155SH DFND13,968,15500
INOGEN INCCOM45780L10419,251601,772SH DFND1601,77200
INSMED INCCOM PAR $.0145766930733,8731,628,531SH DFND11,628,53100
INTEGRA LIFESCIENCES HLDGS CNOTE 1.625%12/1457985AK554,55647,428,000PRN DFND147,428,00000
INVITAE CORPCOM46185L1032,793166,666SH DFND1166,66600
JUNO THERAPEUTICS INCCOM48205A10911,110183,149SH DFND1183,14900
KERYX BIOPHARMACEUTICALS INCCOM4925151019,744765,450SH DFND1765,45000
KINDRED BIOSCIENCES INCCOM4945771091,994279,204SH DFND1279,20400
LOXO ONCOLOGY INCCOM54886210119,8151,591,546SH DFND11,591,54600
LUMENIS LTDSHS CL BM6778Q1215,202434,566SH DFND1434,56600
MAZOR ROBOTICS LTDSPONSORED ADS57886P10347041,861SH DFND141,86100
MCKESSON CORPCOM58155Q10320,81092,000SH DFND192,00000
MEI PHARMA INCCOM NEW55279B2021,437802,568SH DFND1802,56800
MIRATI THERAPEUTICS INCCOM60468T10596532,912SH DFND132,91200
MYLAN N VSHS EURON5946510959410,000SH DFND110,00000
NANOSTRING TECHNOLOGIES INCCOM63009R10914,8841,460,652SH DFND11,460,65200
NEKTAR THERAPEUTICSCOM64026810850245,600SH DFND145,60000
NUVASIVE INCCOM67070410515,554338,194SH DFND1338,19400
NXSTAGE MEDICAL INCCOM67072V10387,7645,073,050SH DFND15,073,05000
ONCOTHYREON INCCOM682324108233143,200SH DFND1143,20000
ORTHOFIX INTL N VCOMN6748L10222,619630,222SH DFND1630,22200
OVASCIENCE INCCOM69014Q10114,139407,108SH DFND1407,10800
OXFORD IMMUNOTEC GLOBAL PLCORD SHSG6855A1037,353522,250SH DFND1522,25000
PACIFIC BIOSCIENCES CALIF INCOM69404D10817,8023,048,310SH DFND13,048,31000
PALATIN TECHNOLOGIES INCCOM PAR $ .016960774032,0402,000,000SH DFND12,000,00000
PARNELL PHARMACEUT HLDGS LTDSHSQ736221041,245253,592SH DFND1253,59200
PLASMATECH BIOPHARMACEUTICAL*W EXP 10/24/20172754H117319375,000SH DFND1375,00000
PLASMATECH BIOPHARMACEUTICALCOM72754H1091,099349,908SH DFND1349,90800
PORTOLA PHARMACEUTICALS INCCOM73701010821,810574,546SH DFND1574,54600
PROQR THRAPEUTICS N VSHS EURON715421094,582209,398SH DFND1209,39800
PROTEON THERAPEUTICS INCCOM74371L10914,7161,265,343SH DFND11,265,34300
RETROPHIN INCCOM7612991063,791158,223SH DFND1158,22300
RIGEL PHARMACEUTICALS INCCOM NEW7665596038,5602,397,855SH DFND12,397,85500
RITE AID CORPCOM76775410445952,764SH DFND152,76400
SAGE THERAPEUTICS INCCOM78667J10829,909595,443SH DFND1595,44300
SCYNEXIS INCCOM8112921014,090492,781SH DFND1492,78100
SPARK THERAPEUTICS INCCOM84652J10348,917631,192SH DFND1631,19200
ST JUDE MED INCCOM7908491033,29450,370SH DFND150,37000
STEADYMED LTDSHSM8492010310,7761,267,733SH DFND11,267,73300
STREAMLINE HEALTH SOLUTIONSCOM86323X1066,4711,822,759SH DFND11,822,75900
SUCAMPO PHARMACEUTICALS INCCL A8649091063,501225,000SH DFND1225,00000
SYNERON MEDICAL LTDORD SHSM872451027,745625,593SH DFND1625,59300
THERAPEUTICSMD INCCOM88338N10713,4512,223,310SH DFND12,223,31000
TONIX PHARMACEUTICALS HLDG CCOM NEW8902602018,6271,365,000SH DFND11,365,00000
TRACON PHARMACEUTICALS INCCOM89237H1006,809485,000SH DFND1485,00000
TRILLIUM THERAPEUTICS INCCOM NEW89620X5064,573226,064SH DFND1226,06400
TRIVASCULAR TECHNOLOGIES INCCOM89685A10210,387990,202SH DFND1990,20200
TRUPANION INCCOM89820210616,8152,101,848SH DFND12,101,84800
UNIVERSAL AMERN CORP NEWCOM91338E10155,3885,186,148SH DFND15,186,14800
VANDA PHARMACEUTICALS INCCOM92165910838,4484,134,157SH DFND14,134,15700
VERSARTIS INCCOM92529L1026,240339,703SH DFND1339,70300
WALGREENS BOOTS ALLIANCE INCCOM93142710843,424512,800SH DFND1512,80000
WEBMD HEALTH CORPNOTE 1.500%12/094770VAK824,43323,000,000PRN DFND123,000,00000
XENCOR INCCOM98401F10529,0401,895,535SH DFND11,895,53500
ZAFGEN INCCOM98885E10341,5981,050,178SH DFND11,050,17800
ZS PHARMA INCCOM98979G1056,202147,385SH DFND1147,38500