The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 24,955 145,000 SH   DFND 1 145,000 0 0
ACUTUS MED INC COM 005111109 23,412 2,648,386 SH   DFND 1 2,648,386 0 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102 188,737 8,103,792 SH   DFND 1 8,103,792 0 0
AERIE PHARMACEUTICALS INC NOTE 1.500%10/0 00771VAB4 143,842 157,390,000 PRN   DFND 1 157,390,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 33,938 2,977,020 SH   DFND 1 2,977,020 0 0
AEROVATE THERAPEUTICS INC COM 008064107 14,986 714,285 SH   DFND 1 714,285 0 0
ALECTOR INC COM 014442107 24,079 1,055,192 SH   DFND 1 1,055,192 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 43,821 3,594,829 SH   DFND 1 3,594,829 0 0
AMERICAN WELL CORP CL A 03044L105 9,029 991,115 SH   DFND 1 991,115 0 0
ANNEXON INC COM 03589W102 10,867 583,913 SH   DFND 1 583,913 0 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 35,498 28,825,000 PRN   DFND 1 28,825,000 0 0
APRIA INC COM 03836A101 52,668 1,417,700 SH   DFND 1 1,417,700 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 9,412 425,300 SH Put DFND 1 425,300 0 0
AVEANNA HEALTHCARE HLDGS INC COM 05356F105 8,124 1,013,007 SH   DFND 1 1,013,007 0 0
BENEFITFOCUS INC NOTE 1.250%12/1 08180DAB2 6,135 6,500,000 PRN   DFND 1 6,500,000 0 0
BIOATLA INC COM 09077B104 13,669 464,300 SH   DFND 1 464,300 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 3,372 234,643 SH   DFND 1 234,643 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 33,106 9,170,699 SH   DFND 1 9,170,699 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 6,431 760,128 SH   DFND 1 760,128 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 19,056 185,354 SH   DFND 1 185,354 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8 110,499 80,000,000 PRN   DFND 1 80,000,000 0 0
BROOKDALE SR LIVING INC COM 112463104 33,093 5,252,800 SH   DFND 1 5,252,800 0 0
BUTTERFLY NETWORK INC *W EXP 02/12/202 124155110 2,017 733,333 SH   DFND 1 733,333 0 0
CABALETTA BIO INC COM 12674W109 5,645 464,252 SH   DFND 1 464,252 0 0
CAREMAX INC COM CL A 14171W103 162,083 16,778,750 SH   DFND 1 16,778,750 0 0
CAREMAX INC *W EXP 06/08/202 14171W111 1,900 672,000 SH   DFND 1 672,000 0 0
CENTENE CORP DEL COM 15135B101 62,547 1,003,800 SH   DFND 1 1,003,800 0 0
COGENT BIOSCIENCES INC COM 19240Q201 13,464 1,601,000 SH   DFND 1 1,601,000 0 0
CUE HEALTH INC COM 229790100 9,435 798,867 SH   DFND 1 798,867 0 0
CULLINAN ONCOLOGY INC COM 230031106 23,563 1,044,000 SH   DFND 1 1,044,000 0 0
CVRX INC COM 126638105 6,843 413,747 SH   DFND 1 413,747 0 0
CYTOKINETICS INC COM NEW 23282W605 54,924 1,536,758 SH   DFND 1 1,536,758 0 0
DA32 LIFE SCNCE TEC ACQSTN C CLASS A COM 23312M106 15,728 1,600,000 SH   DFND 1 1,600,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 40,596 1,710,730 SH   DFND 1 1,710,730 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 27,694 815,000 SH   DFND 1 815,000 0 0
DEFINITIVE HEALTHCARE CORP CLASS A COM 24477E103 10,708 250,000 SH   DFND 1 250,000 0 0
DELCATH SYS INC COM NEW 24661P807 5,220 500,000 SH   DFND 1 500,000 0 0
DFP HEALTHCARE ACQUISITNS CO COM CL A 23343Q100 49,700 5,000,000 SH   DFND 1 5,000,000 0 0
DFP HEALTHCARE ACQUISITNS CO *W EXP 03/31/202 23343Q118 2,013 1,250,000 SH   DFND 1 1,250,000 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 65,290 3,933,137 SH   DFND 1 3,933,137 0 0
ENVISTA HOLDINGS CORPORATION NOTE 2.375% 6/0 29415FAB0 109,205 52,500,000 PRN   DFND 1 52,500,000 0 0
ERASCA INC COM 29479A108 16,693 786,660 SH   DFND 1 786,660 0 0
EUCRATES BIOMEDICAL ACQU COR UNIT 10/23/2027 G3141W114 9,950 1,000,000 SH   DFND 1 1,000,000 0 0
FATE THERAPEUTICS INC COM 31189P102 21,456 362,000 SH   DFND 1 362,000 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 8,943 405,416 SH   DFND 1 405,416 0 0
GLAUKOS CORP NOTE 2.750% 6/1 377322AB8 129,642 108,000,000 PRN   DFND 1 108,000,000 0 0
GLAUKOS CORP COM 377322102 29,817 619,000 SH   DFND 1 619,000 0 0
GRAPHITE BIO INC COM 38870X104 14,854 906,308 SH   DFND 1 906,308 0 0
GRAYBUG VISION INC COM SHS 38942Q103 17,535 5,281,713 SH   DFND 1 5,281,713 0 0
HEALTH CATALYST INC NOTE 2.500% 4/1 42225TAB3 26,292 15,000,000 PRN   DFND 1 15,000,000 0 0
IGNYTE ACQUISITION CORP *W EXP 01/05/202 45175H114 232 362,500 SH   DFND 1 362,500 0 0
IGNYTE ACQUISITION CORP COM 45175H106 7,098 725,000 SH   DFND 1 725,000 0 0
INOZYME PHARMA INC COM 45790W108 27,176 2,344,786 SH   DFND 1 2,344,786 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 51,712 50,000,000 PRN   DFND 1 50,000,000 0 0
INSMED INC NOTE 0.750% 6/0 457669AB5 55,120 50,000,000 PRN   DFND 1 50,000,000 0 0
INSTIL BIO INC COM 45783C101 19,944 1,115,739 SH   DFND 1 1,115,739 0 0
INSULET CORP NOTE 0.00375 9/0 45784PAK7 80,407 57,581,000 PRN   DFND 1 57,581,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 52,121 57,791,000 PRN   DFND 1 57,791,000 0 0
INVITAE CORP NOTE 2.000% 9/0 46185LAB9 199,645 163,385,000 PRN   DFND 1 163,385,000 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 3,529 60,271 SH   DFND 1 60,271 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 20,993 694,667 SH   DFND 1 694,667 0 0
IVERIC BIO INC COM 46583P102 78,987 4,863,725 SH   DFND 1 4,863,725 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 37,754 2,163,554 SH   DFND 1 2,163,554 0 0
KINNATE BIOPHARMA INC COM 49705R105 23,676 1,028,508 SH   DFND 1 1,028,508 0 0
KURA ONCOLOGY INC COM 50127T109 43,368 2,315,417 SH   DFND 1 2,315,417 0 0
LARIMAR THERAPEUTICS INC COM 517125100 67,223 5,830,249 SH   DFND 1 5,830,249 0 0
LEAP THERAPEUTICS INC COM 52187K101 16,040 4,000,000 SH   DFND 1 4,000,000 0 0
MEDAVAIL HOLDINGS INC COM 58406B103 3,336 1,142,552 SH   DFND 1 1,142,552 0 0
MEDTECH ACQUISITION CORP COM CL A 58507N105 9,930 999,999 SH   DFND 1 999,999 0 0
MEDTECH ACQUISITION CORP *W EXP 12/22/202 58507N113 273 333,333 SH   DFND 1 333,333 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 39,694 2,063,083 SH   DFND 1 2,063,083 0 0
METACRINE INC COM 59101E103 952 277,469 SH   DFND 1 277,469 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 65,396 3,282,912 SH   DFND 1 3,282,912 0 0
MOLINA HEALTHCARE INC COM 60855R100 62,883 231,776 SH   DFND 1 231,776 0 0
MONTES ARCHIMEDES ACQUISITIO *W EXP 99/99/999 612657114 1,490 1,000,000 SH   DFND 1 1,000,000 0 0
MONTES ARCHIMEDES ACQUISITIO COM CL A 612657106 18,700 2,000,000 SH   DFND 1 2,000,000 0 0
NATERA INC NOTE 2.250% 5/0 632307AB0 135,236 45,000,000 PRN   DFND 1 45,000,000 0 0
NATERA INC NOTE 2.250% 5/0 670002AB0 43,056 25,000,000 PRN   DFND 1 25,000,000 0 0
NEOGENOMICS INC NOTE 0.250% 1/1 64049MAB6 2,514 2,500,000 PRN   DFND 1 2,500,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 109,569 1,142,415 SH   DFND 1 1,142,415 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 34,876 26,000,000 PRN   DFND 1 26,000,000 0 0
NUVASIVE INC NOTE 0.00375 3/1 670704AJ4 54,110 55,800,000 PRN   DFND 1 55,800,000 0 0
NUVASIVE INC NOTE 0.01 6/0 670704AL9 98,794 96,966,000 PRN   DFND 1 96,966,000 0 0
NUVATION BIO INC COM CL A 67080N101 35,558 3,577,233 SH   DFND 1 3,577,233 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 427 166,666 SH   DFND 1 166,666 0 0
NUVALENT INC COM 670703107 436,140 19,341,024 SH   DFND 1 19,341,024 0 0
NYXOAH S A SHS B6S7WD106 8,797 300,800 SH   DFND 1 300,800 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106 7,474 271,191 SH   DFND 1 271,191 0 0
ONCORUS INC COM 68236R103 29,411 3,148,977 SH   DFND 1 3,148,977 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 15,984 6,949,416 SH   DFND 1 6,949,416 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 106,267 7,462,543 SH   DFND 1 7,462,543 0 0
ORION ACQUISITION CORP *W EXP 02/19/202 68626A116 80 125,000 SH   DFND 1 125,000 0 0
ORION ACQUISITION CORP COM CL A 68626A108 4,850 500,000 SH   DFND 1 500,000 0 0
OUTSET MED INC COM 690145107 19,807 400,622 SH   DFND 1 400,622 0 0
PACIRA BIOSCIENCES INC COM 695127100 54,165 967,236 SH   DFND 1 967,236 0 0
PACIRA BIOSCIENCES INC NOTE 0.750% 8/0 695127AF7 87,723 81,600,000 PRN   DFND 1 81,600,000 0 0
PHARVARIS N V COM N69605108 28,518 1,608,471 SH   DFND 1 1,608,471 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 23,959 804,000 SH   DFND 1 804,000 0 0
PRIVIA HEALTH GROUP INC COM 74276R102 7,068 300,000 SH   DFND 1 300,000 0 0
PROFOUND MED CORP COM NEW 74319B502 19,000 1,297,797 SH   DFND 1 1,297,797 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 24,702 1,394,000 SH   DFND 1 1,394,000 0 0
PTC THERAPEUTICS INC NOTE 0.03 8/1 69366JAB7 15,061 14,527,000 PRN   DFND 1 14,527,000 0 0
PULMONX CORP COM 745848101 73,035 2,029,887 SH   DFND 1 2,029,887 0 0
QUANTUM SI INC COM CL A 74765K105 11,676 1,400,000 SH   DFND 1 1,400,000 0 0
QUANTUM SI INC *W EXP 06/10/202 74765K113 677 333,333 SH   DFND 1 333,333 0 0
RENEO PHARMACEUTICALS INC COM 75974E103 6,327 849,300 SH   DFND 1 849,300 0 0
REVOLUTION HEALTHCAR AQ CORP CLASS A COM 76155Y108 9,710 1,000,000 SH   DFND 1 1,000,000 0 0
REVOLUTION HEALTHCAR AQ CORP *W EXP 12/31/202 76155Y116 186 200,000 SH   DFND 1 200,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 43,073 1,565,712 SH   DFND 1 1,565,712 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 25,985 1,989,625 SH   DFND 1 1,989,625 0 0
RXSIGHT INC COM 78349D107 11,403 900,000 SH   DFND 1 900,000 0 0
SARISSA CAPITAL ACQUISITN CO UNIT 10/23/2027 G7823W128 9,876 1,000,000 SH   DFND 1 1,000,000 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 105,110 13,848,488 SH   DFND 1 13,848,488 0 0
SENIOR CONNECT ACQUISITN COR *W EXP 12/31/202 81723H116 355 500,000 SH   DFND 1 500,000 0 0
SENIOR CONNECT ACQUISITN COR COM CL A 81723H108 9,770 1,000,000 SH   DFND 1 1,000,000 0 0
SILK RD MED INC COM 82710M100 54,494 990,251 SH   DFND 1 990,251 0 0
SINGULAR GENOMICS SYSTEMS IN COM 82933R100 101,963 9,112,019 SH   DFND 1 9,112,019 0 0
SOMALOGIC INC *W EXP 03/01/202 83444K113 414 120,000 SH   DFND 1 120,000 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 32,397 510,673 SH   DFND 1 510,673 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 13,222 2,200,000 SH   DFND 1 2,200,000 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 190 166,666 SH   DFND 1 166,666 0 0
TABULA RASA HEALTHCARE INC NOTE 1.750% 2/1 873379AA9 37,450 45,000,000 PRN   DFND 1 45,000,000 0 0
TALKSPACE INC COM 87427V103 2,738 750,000 SH   DFND 1 750,000 0 0
TERNS PHARMACEUTICALS INC COM 880881107 24,445 2,345,959 SH   DFND 1 2,345,959 0 0
TURMERIC ACQUISITION CORP UNIT 10/08/2025 G9127T116 7,448 750,000 SH   DFND 1 750,000 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 5,570 83,846 SH   DFND 1 83,846 0 0
TYRA BIOSCIENCES INC COM 90240B106 10,994 625,000 SH   DFND 1 625,000 0 0
VIATRIS INC COM 92556V106 255,065 18,824,000 SH   DFND 1 18,824,000 0 0
VINCERX PHARMA INC COM NEW 92731L106 22,303 1,379,310 SH   DFND 1 1,379,310 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 15,750 3,214,340 SH   DFND 1 3,214,340 0 0
WEREWOLF THERAPEUTICS INC COM 95075A107 30,078 1,752,787 SH   DFND 1 1,752,787 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 42 20,148 SH   DFND 1 20,148 0 0
XERIS PHARMACEUTICALS INC NOTE 5.000% 7/1 98422LAA5 18,864 18,000,000 PRN   DFND 1 18,000,000 0 0