Liability Related to Sale of Future Royalties - Schedule of Activity Within Liability Related to Sale of Future Royalties (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Liability Related to Sale of Future Royalties [Line Items]
Non-cash royalty revenue payable to HCRP	$ (12,106)	$ (11,486)
Royalty Purchase Agreement
Liability Related to Sale of Future Royalties [Line Items]
Liability related to sale of future royalties - beginning balance	15,257	24,401
Deferred transaction costs amortized	234	401
Non-cash royalty revenue payable to HCRP	(12,106)	(11,486)
Non-cash interest expense recognized	1,075	1,941
Liability related to sale of future royalties - ending balance	$ 4,460	$ 15,257