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Common Stock Options and Restricted Stock - Additional Information (Details)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2021
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
$ / shares
shares
Sep. 30, 2020
shares
Sep. 17, 2020
shares
Dec. 31, 2019
shares
Jun. 19, 2019
$ / shares
shares
Share-based compensation expense            
Reverse stock split, description   1-for-6 reverse stock split        
Stockholders' equity note, stock split, conversion ratio   0.167        
Common stock, Authorized shares 61,666,666 61,666,666   61,666,666 13,333,333  
Common stock, par value (in dollars per share) | $ / shares $ 0.001 $ 0.001        
Options granted (in shares) 336,000          
Weighted average exercise price | $ / shares $ 94.38 $ 127.13        
Share-based compensation expense recognized | $ $ 2,995 $ 8,100        
Total unrecognized compensation costs related to unvested stock options and restricted stock awards that the company expects to recognize | $   $ 1,600        
Weighted average period 3 years 3 months 18 days          
Stock Options | Employees and Directors            
Share-based compensation expense            
Weighted average fair value of options granted (in dollars per share) | $ / shares $ 2.57 $ 3.95        
Options granted (in shares) 596,795          
Weighted average exercise price | $ / shares $ 3.72          
Total compensation charge to be recognized over service period | $ $ 2,000          
Share-based compensation expense recognized | $ $ 900          
Stock Options | Non Employee            
Share-based compensation expense            
Options granted (in shares) 0 0        
Stock Options and Restricted Stock Awards            
Share-based compensation expense            
Compensation costs capitalized in inventory balances | $ $ 0 $ 300        
Stock Options and Restricted Stock Awards | Employees and Directors            
Share-based compensation expense            
Share-based compensation expense recognized | $ $ 3,000 $ 8,100        
The 2006 Plan            
Share-based compensation expense            
Expiration period 10 years          
Number of shares authorized for issuance   2,485,342        
Aggregate restricted stock granted (in shares) 1,955,881          
Remaining restricted stock subject to outstanding options (in shares) 313,569          
The 2015 Plan            
Share-based compensation expense            
Expiration period 10 years          
Number of shares authorized for issuance 1,350,000          
Aggregate restricted stock granted (in shares) 1,408,784          
Remaining restricted stock subject to outstanding options (in shares) 701,976          
The 2016 Plan            
Share-based compensation expense            
Options Issued 170,000          
The 2019 ESPP Plan            
Share-based compensation expense            
Common stock, Authorized shares 250,000         250,000
Common stock, par value (in dollars per share) | $ / shares           $ 0.001
Previously Reported            
Share-based compensation expense            
Common stock, Authorized shares     370,000,000   80,000,000