Property and Equipment - Schedule of Property and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020
Property and Equipment
Property and equipment	$ 39,379	$ 43,287
Less accumulated depreciation	(34,997)	(36,024)
Property and equipment, net	$ 4,382	7,263
Minimum
Property and Equipment
Estimated useful lives used	1 year
Maximum
Property and Equipment
Estimated useful lives used	7 years
Machinery and equipment
Property and Equipment
Property and equipment	$ 2,315	2,569
Machinery and equipment \| Minimum
Property and Equipment
Estimated useful lives used	2 years
Machinery and equipment \| Maximum
Property and Equipment
Estimated useful lives used	7 years
Leasehold improvements
Property and Equipment
Property and equipment	$ 15,317	15,317
Estimated useful lives used	Lesser of useful life or remaining lease term
Computer equipment
Property and Equipment
Property and equipment	$ 17,973	17,758
Computer equipment \| Minimum
Property and Equipment
Estimated useful lives used	1 year
Computer equipment \| Maximum
Property and Equipment
Estimated useful lives used	3 years
Laboratory equipment
Property and Equipment
Property and equipment	$ 1,644	5,343
Laboratory equipment \| Minimum
Property and Equipment
Estimated useful lives used	2 years
Laboratory equipment \| Maximum
Property and Equipment
Estimated useful lives used	5 years
Furniture and fixtures
Property and Equipment
Property and equipment	$ 2,130	2,129
Furniture and fixtures \| Minimum
Property and Equipment
Estimated useful lives used	4 years
Furniture and fixtures \| Maximum
Property and Equipment
Estimated useful lives used	7 years
Construction In Progress
Property and Equipment
Property and equipment		$ 171

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Describes the periods of time over which an entity anticipates to receive utility from its property, plant and equipment (that is, the periods of time over which an entity allocates the initial cost of its property, plant and equipment).

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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