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Acquisitions - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 8 Months Ended 12 Months Ended 20 Months Ended
May 04, 2016
Sep. 30, 2016
Apr. 18, 2016
Dec. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2017
Apr. 18, 2017
Jun. 30, 2016
Acquisitions                    
Goodwill       $ 280,599 $ 286,611 $ 280,599   $ 286,611    
Net revenues         588,287 519,601 $ 492,660      
Net (loss) income         (223,359) (35,603) 11,058      
Biotie Therapies Corp.                    
Acquisitions                    
Voting interest acquired (as a percent)     93.00%              
Aggregate equity purchase price     $ 350,000              
Additional voting interest acquired (as a percent) 4.00% 3.00%                
Purchase consideration for subsequent acquisition $ 14,500                  
Voting interest acquired including subsequent acquisition (as a percent)   100.00%               97.00%
Payment of cash security deposit   $ 13,500                
Proceeds from refund of cash security deposit         2,700          
Goodwill       103,876   103,876     $ 97,455  
Acquisition-related expenses         600 17,600 $ 400 18,600    
Goodwill deductible for tax purposes     $ 0              
Net revenues       2,700            
Net (loss) income       (37,500)            
Biotie Therapies Corp. | Foreign currency option                    
Acquisitions                    
Notional value of foreign currency option       0 0 0   $ 0    
Biotie Therapies Corp. | Foreign currency option | Other income                    
Acquisitions                    
Realized gain on foreign currency options           9,900        
Biotie Therapies Corp. | Final Measurement Period Adjustments                    
Acquisitions                    
Goodwill       $ 1,200   $ 1,200     $ (6,421)  
Final measurement period adjustments         6,400          
Increase in deferred tax liabilities         200          
Biotie Therapies Corp. | Final Measurement Period Adjustments | Non-convertible Capital Loans                    
Acquisitions                    
Final measurement period adjustments         (2,700)          
Biotie Therapies Corp. | Final Measurement Period Adjustments | Convertible Capital Loans                    
Acquisitions                    
Final measurement period adjustments         $ (3,800)