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Summary of Significant Accounting Policies - Additional Information (Details)
3 Months Ended 12 Months Ended
Oct. 01, 2017
USD ($)
Sep. 30, 2015
USD ($)
Dec. 31, 2017
USD ($)
Item
Customer
Segment
Dec. 31, 2016
USD ($)
Item
Customer
Dec. 31, 2015
Customer
Other Comprehensive Income (Loss)          
Foreign currency translation adjustment, Tax     $ 0 $ 0  
Foreign currency translation adjustment     $ 19,759,000 (12,901,000)  
Revenue Recognition          
Net adjustment from previously deferred product sales   $ 22,200,000      
Number of specialty distributors for Qutenza | Item     2    
Allowance for Cash Discounts          
Time period needed typically to settle cash discounts     34 days    
Allowance for cash discounts     $ 6,900,000 5,700,000  
Accrual for allowance for cash discounts     800,000 $ 600,000  
Allowance for Doubtful Accounts          
Allowance related to credit risk     $ 0    
Number of customer to whom an allowance for doubtful accounts recognized | Item       1  
Allowance for doubtful accounts related to one customer       $ 400,000  
Segment and Geographic Information          
Number of operating segments | Segment     1    
Number of reportable operating segments | Segment     1    
Accounting Standards Update 2016-09          
Segment and Geographic Information          
Adjustment to accumulated deficit     $ 12,100,000    
Income tax expense associated with stock compensation shortfalls and forfeitures     $ 4,500,000    
Product revenue          
Revenue Recognition          
Number of customers | Customer     4 3 3
Accounts receivable          
Revenue Recognition          
Number of customers | Customer     4 3  
Customers | Product revenue          
Revenue Recognition          
Concentration risk, percentage     82.00%    
Customers | Accounts receivable          
Revenue Recognition          
Concentration risk, percentage     69.00%    
Ampyra          
Revenue Recognition          
Contractually obligated inventory holdings period     20 days    
Royalty Agreement          
Non-Cash Interest Expense on Liability Related to Sale of Future Royalties          
Non cash royalty payment received $ 40,000,000        
Estimated effective annual interest rate     15.00%    
Minimum          
Property and Equipment          
Estimated useful lives     1 year    
Minimum | Supply agreement | Alkermes License Agreement          
Revenue Recognition          
Compensatory Payments Purchase Requirements Threshold Percentage     75.00%    
Maximum          
Property and Equipment          
Estimated useful lives     7 years    
Maximum | Supply agreement | Alkermes License Agreement          
Revenue Recognition          
Compensatory Payments Purchase Requirements Threshold Percentage     100.00%    
Maximum | Supply agreement | Patheon Inc Second Manufacturing agreement          
Revenue Recognition          
Compensatory Payments Purchase Requirements Threshold Percentage     25.00%    
Letters of Credit          
Restricted Cash          
Restricted Cash and Cash Equivalents     $ 600,000