Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 307,068	$ 158,537
Restricted cash	410	79
Trade accounts receivable, net of allowances of $845 and $964, as of December 31, 2017 and 2016, respectively	81,403	52,239
Prepaid expenses	13,333	12,907
Finished goods inventory held by the Company	37,501	43,135
Other current assets	1,983	5,760
Total current assets	441,698	272,657
Property and equipment, net of accumulated depreciation	36,669	34,310
Goodwill	286,611	280,599
Deferred tax asset		4,400
Intangible assets, net of accumulated amortization	430,603	742,242
Non-current portion of deferred cost of license revenue	1,638	2,272
Other assets	750	5,855
Total assets	1,197,969	1,342,335
Current liabilities:
Accounts payable	27,367	26,933
Accrued expenses and other current liabilities	100,128	104,890
Current portion of deferred license revenue	9,057	9,057
Current portion of loans payable	645	6,256
Current portion of liability related to sale of future royalties	6,763
Current portion of convertible notes payable		765
Total current liabilities	143,960	147,901
Convertible senior notes (due 2021)	308,805	299,395
Acquired contingent consideration	112,722	72,100
Non-current portion of deferred license revenue	23,398	32,456
Non-current portion of loans payable	25,670	24,635
Deferred tax liability	22,459	92,807
Non-current portion of liability related to sale of future royalties	29,025
Other non-current liabilities	11,943	8,830
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.001 par value. Authorized 1,000,000 shares at December 31, 2017 and no shares at December 31, 2016; no shares issued as of December 31, 2017
Common stock, $0.001 par value. Authorized 80,000,000 shares at December 31, 2017 and 2016; issued 46,441,428 and 45,680,042 shares, including those held in treasury, as of December 31, 2017 and 2016, respectively	46	46
Treasury stock at cost (16,151 and 12,420 shares at December 31, 2017 and 2016, respectively)	(389)	(329)
Additional paid-in capital	968,580	921,365
Accumulated deficit	(455,108)	(243,970)
Accumulated other comprehensive income (loss)	6,858	(12,901)
Total stockholders’ equity	519,987	664,211
Total liabilities and stockholders’ equity	$ 1,197,969	$ 1,342,335