Income Taxes - Schedule of Reconciliation of the Statutory U.S. Federal Income Tax Rate to the Entity's Effective Income Tax Rate (Details)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Reconciliation of statutory federal income tax rate to effective income tax rate
U.S. federal statutory tax rate	21.00%	21.00%
State and local income taxes	(0.30%)	0.40%
Stock option compensation	(0.20%)	(0.10%)
Stock option shortfall	(8.80%)	(5.00%)
GILTI Inclusion	(8.30%)
Uncertain tax positions	0.40%	0.50%
Other nondeductible and permanent differences	(7.70%)	(2.60%)
U.S. write-off/expiration	(255.80%)
Valuation allowance, net of foreign tax rate differential	151.60%	(9.50%)
Biotie Finland cancellation of debt exclusion	21.70%
Federal return to provision differences	(0.60%)
Effective income tax rate	(87.00%)	4.70%