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License, Research and Collaboration Agreements - Supply Agreement - Additional Information (Details) - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Sep. 30, 2022
Oct. 31, 2022
Dec. 31, 2022
Dec. 31, 2020
Alkermes        
Supply Agreement        
Licensing royalties, awarded amount   $ 18.3    
Alkermes License Agreement        
Supply Agreement        
Cost Of License Payable       $ 15.0
Biogen        
Supply Agreement        
Additional payments based on the successful achievement of future regulatory or sales milestones       $ 300.0
Supply agreement | Alkermes        
Supply Agreement        
Licensing royalties, awarded amount   $ 18.3    
Supply agreement | Maximum | Patheon Inc Second Manufacturing agreement        
Supply Agreement        
Purchase requirements threshold percentage 25.00%      
Supply agreement | Alkermes License Agreement | Ampyra | Alkermes        
Supply Agreement        
Minimum agreed percentage of annual requirements for purchase     75.00%  
Supply agreement | Alkermes License Agreement | Maximum        
Supply Agreement        
Purchase requirements threshold percentage     100.00%