Leases - Additional Information (Details)	1 Months Ended	12 Months Ended
	Mar. 31, 2023 USD ($)	Dec. 31, 2022 USD ($) ft²	Jun. 30, 2022 ft²	Dec. 31, 2021 USD ($)	Dec. 31, 2018 ft²	Oct. 31, 2016 USD ($) ft²
Operating Lease Information
Right-of-use assets		$ 5,287,000		$ 6,751,000
Lease liabilities		$ 5,886,000
Operating lease description		Operating lease ROU assets and operating lease liabilities are recognized based on the present value of the future minimum lease payments over the lease term at the commencement date. The operating lease ROU asset also includes any lease payments made and excludes lease incentives and initial direct costs incurred, if any. The Company’s leases have remaining lease terms of 4 years to 5.5 years.
Operating lease weighted-average remaining lease term		4 years 4 months 24 days
Operating lease weighted-average discount rate		7.92%
Ardsley, New York
Operating Lease Information
Area of leased property | ft²		160,000
Termination option effective date		Jun. 22, 2022
Termination Fee		$ 4,700,000
Pearl River, New York
Operating Lease Information
Lease term			6 years
Area of leased property | ft²			21,000
Operating sublease, existence of option to extend		false
Base Rent		$ 0
Base rent payment commencing on January 1, 2023		$ 300,000
Base rent subject to annual escalation percentage		2.00%
Chelsea, Massachusetts | Manufacturing Facility
Operating Lease Information
Area of leased property | ft²					95,000
Contribution of fund agreed		$ 2,000,000
Chelsea, Massachusetts | Manufacturing Facility | Subsequent event
Operating Lease Information
Contribution of fund agreed	$ 2,000,000
Waltham, MA | Office and Laboratory Space
Operating Lease Information
Lease term						10 years
Area of leased property | ft²						26,000
Base Rent						$ 1,200,000
Minimum
Operating Lease Information
Operating lease remaining lease term		4 years
Maximum
Operating Lease Information
Operating lease remaining lease term		5 years 6 months