X0202 4 2005-05-31 0 0001217688 FOXHOLLOW TECHNOLOGIES, INC. FOXH 0001007708 SIMPSON JOHN B PH D MD C/O FOXHOLLOW TECHNOLOGIES, INC. 740 BAY ROAD REDWOOD CITY CA 94063 1 0 1 0 Common Stock 2005-05-31 4 S 0 100000 35.7159 D 4915488 I By Simpson Family Trust Common Stock 2005-05-31 4 S 0 39073 35.411 D 4876415 I By Simpson Family Trust Common Stock 2005-05-31 4 S 0 7000 35.4110 D 529427 I By JD Simpson Trust Common Stock 2005-05-31 4 S 0 2700 36.5 D 526727 I By JD Simpson Trust Common Stock 56546 I By Spouse Common Stock 204733 I By Fox Hollow, LP Common Stock 250000 I By John B. Simpson Annuity Trust Common Stock 250000 I By Rita Lynn Simpson Annuity Trust The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by John Bush Simpson and Rita Lynn Simpson, Trustees of the Simpson Family Trust U/D/T 1/12/90 on February 25, 2005. Dr. Simpson disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by John David Simpson Trust II on February 25, 2005. These shares are held in a trust for the benefit of Dr. Simpson's son of which Dr. Simpson serves as a trustee. Dr. Simpson disclaims beneficial ownership of these shares, and the filing of this report is not an admission that Dr. Simpson is a beneficial owner of these shares for purposes of Section 16 or for any other purpose. * This report does not include 452,568 and 89,572 shares held by De Novo (Q) Ventures I, L.P. and De Novo Ventures I, L.P., respectively, following a pro rata distribution of 1,301,015 shares by De Novo (Q) Ventures I, L.P. and 257,421 shares by De Novo Ventures I, L.P. to each of its limited partners. Dr. Simpson no longer has any voting or dispositive control over shares held by De Novo (Q) Ventures I, L.P. and De Novo Ventures I, L.P. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. /s/ John B. Simpson 2005-06-02