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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 Sm9h+wXk0hwvSE6wpm3y+pnnjGApxMTN7Zo7+NmDFTK1btHTTK1hZf018HPEGGEX
 ZOiLbZ3dqRAItiIylQ3img==

<SEC-DOCUMENT>0001225208-11-003889.txt : 20110127
<SEC-HEADER>0001225208-11-003889.hdr.sgml : 20110127
<ACCEPTANCE-DATETIME>20110127133925
ACCESSION NUMBER:		0001225208-11-003889
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20110127
FILED AS OF DATE:		20110127
DATE AS OF CHANGE:		20110127

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BANK OF SOUTH CAROLINA CORP
		CENTRAL INDEX KEY:			0001007273
		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
		IRS NUMBER:				571021355
		STATE OF INCORPORATION:			SC
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		256 MEETING ST
		STREET 2:		P O BOX 538
		CITY:			CHARLESTON
		STATE:			SC
		ZIP:			29402
		BUSINESS PHONE:		803 724 1500

	MAIL ADDRESS:	
		STREET 1:		256 MEETING STREET
		CITY:			CHARLESTON
		STATE:			SC
		ZIP:			29402

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Huger Katherine M
		CENTRAL INDEX KEY:			0001244474

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-27702
		FILM NUMBER:		11551549

	MAIL ADDRESS:	
		STREET 1:		P O BOX 538
		CITY:			CHARLESTON
		STATE:			SC
		ZIP:			29402

	FORMER NAME:	
		FORMER CONFORMED NAME:	HUGER KATHERINE M
		DATE OF NAME CHANGE:	20030619
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>doc4.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2011-01-27</periodOfReport>

    <issuer>
        <issuerCik>0001007273</issuerCik>
        <issuerName>BANK OF SOUTH CAROLINA CORP</issuerName>
        <issuerTradingSymbol>BKSC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001244474</rptOwnerCik>
            <rptOwnerName>Huger Katherine M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P. O. BOX 538</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CHARLESTON</rptOwnerCity>
            <rptOwnerState>SC</rptOwnerState>
            <rptOwnerZipCode>29402-0538</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8052.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>804.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Spouse</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>Filing is for the purpose of restating balances.  Balances were adjusted for a 09/24/10 10% stock dividend; adjustment was applied 09/24/10.</remarks>

    <ownerSignature>
        <signatureName>Janice B. Stanley, Attorney in Fact</signatureName>
        <signatureDate>2011-01-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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