SIGNIFICANT ACCOUNTING POLICIES (Details) $ / shares in Units, $ in Thousands						1 Months Ended	3 Months Ended
	Feb. 27, 2023 USD ($)	Jul. 02, 2021 USD ($) $ / shares shares	May 13, 2021 USD ($)	Jul. 23, 2018 USD ($)	Oct. 19, 2017 USD ($)	Oct. 31, 2015	Mar. 31, 2023 USD ($) agreement $ / shares shares	Mar. 31, 2022 $ / shares shares
Significant Accounting Policies [Line Items]
Common Stock, Par or Stated Value Per Share | $ / shares							$ 0.001	$ 0.001
Stock issuance proceeds							$ 14,233
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | shares							36,292,208	33,004,217
ATM Shares
Significant Accounting Policies [Line Items]
Number of shares issued (in shares) | shares							13,980,060
Common Stock, Par or Stated Value Per Share | $ / shares		$ 0.001
Sale of stock, maximum offering price	$ 20,000	$ 20,000					$ 16,500
Stock issuance proceeds							$ 20,000
ATM Equity Offering Sales Agreement
Significant Accounting Policies [Line Items]
Number of shares issued (in shares) | shares		3,296,123					8,212,482
Stock issuance proceeds		$ 13,800					$ 14,900
2024 Notes
Significant Accounting Policies [Line Items]
Interest rate (as a percent)							7.50%
Maintain of Minimum Cash Balance							$ 7,500
Amended Pfizer Agreement | Protalix Bio Therapeutics Incorporation | Brazil
Significant Accounting Policies [Line Items]
Collaborative Arrangement Revenues and Expenses Sharing Percentage						100.00%
Chiesi Agreements
Significant Accounting Policies [Line Items]
Revenue, Performance Obligation, Number | agreement							2
Chiesi US Agreement
Significant Accounting Policies [Line Items]
Additional Amounts Payable To Cover Development Costs				$ 20,000
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones				$ 760,000
Chiesi US Agreement | Minimum
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage				15.00%
Chiesi US Agreement | Maximum
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage				40.00%
Chiesi Ex-US Agreement
Significant Accounting Policies [Line Items]
Additional Amounts Payable To Cover Development Costs					$ 25,000
Agreement Amendment Payment Receivable			$ 10,000
Change In Amount Receivable For Achievement Of Regulatory And Commercial Milestones			$ 25,000
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones					$ 320,000
Chiesi Ex-US Agreement | Minimum
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage					15.00%
Chiesi Ex-US Agreement | Maximum
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage					35.00%
Chiesi US Agreement and Chiesi Ex-US Agreement
Significant Accounting Policies [Line Items]
Non-refundable Payment Receivable				$ 25,000	$ 25,000