SUBSEQUENT EVENTS (Details) - USD ($) $ in Thousands					2 Months Ended	12 Months Ended
	Feb. 07, 2023	Jan. 15, 2023	Jan. 12, 2023	Feb. 17, 2021	Feb. 28, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Subsequent Event [Line Items]
Issuance of common stock under the Sales Agreement, net						$ 8,236	$ 8,575	$ 4,867
Number of shares issued (in shares)				8,749,999
Over-Allotment Option
Subsequent Event [Line Items]
Number of shares issued (in shares)				1,141,304
Subsequent Event
Subsequent Event [Line Items]
Issuance of common stock under the Sales Agreement, net					$ 5,500
Issuance of common stock under the Sales Agreement, net (in shares)					3,590,813
Subsequent Event | Pfizer Agreement [Member]
Subsequent Event [Line Items]
Proceeds From Sale Of Products		$ 1,100
Subsequent Event | Chiesi Agreements
Subsequent Event [Line Items]
Proceeds from expense reimbursements			$ 1,100
Subsequent Event | Brazil Agreement with Fiocruz | Alfataliglicerase
Subsequent Event [Line Items]
Proceeds From Sale Of Products	$ 2,300