The total amount payable to entity for the achievement of regulatory and commercial milestones.

No definition available.

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- Definition

The maximum amount payable to the entity to cover development costs under agreement.

+ References

No definition available.

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- Definition

Agreement Amendment Payment Receivable

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No definition available.

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- Definition

Collaborative arrangement profit sharing percentage.

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No definition available.

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- Definition

The maximum amount payable to entity to cover development costs in any year under agreement.

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No definition available.

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- Definition

Amount of non refundable payment received for future service.

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No definition available.

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- Definition

The cash inflow from consideration received for development services performed.

+ References

No definition available.

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- Definition

Represents the payment as a percentage of future net sales.

+ References

No definition available.

+ Details

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- Definition

The cash inflow in connection with performance of additional studies.

+ References

No definition available.

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- Definition

The amount of upfront, non refundable and non creditable payment receivable under the agreement for licensing rights.

+ References

No definition available.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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- Definition

Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.

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- Definition

Face (par) amount of debt instrument at time of issuance.

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- Definition

Sum of the carrying values as of the balance sheet date of the portions of long-term notes payable due within one year or the operating cycle if longer.

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Amount of cash inflow (outflow) from long-term debt supported by a written promise to pay an obligation.

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No definition available.

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The cash outflow for a borrowing supported by a written promise to pay an obligation.

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COMMERCIALIZATION AGREEMENTS (Details) - USD ($)			1 Months Ended				12 Months Ended
COMMERCIALIZATION AGREEMENTS (Details) - USD ($)	Mar. 29, 2021	Mar. 16, 2020	Sep. 30, 2020	Mar. 31, 2020	Jul. 23, 2018	Oct. 19, 2017	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Jun. 30, 2021	May 13, 2021	Oct. 31, 2015	Nov. 30, 2009
Payment for promissory note							$ 0	$ 4,086,000	$ 215,000
Pfizer
Collaborative Arrangement Profit Share Percentage													40.00%
Debt Instrument, Face Amount												$ 4,300,000
Promissory note			$ 4,300,000
Payment on notes payable			$ 430,000
Payment for promissory note	$ 4,000,000.0
Chiesi US Agreement and Chiesi Ex-US Agreement
Non-refundable Payment Receivable					$ 25,000,000.0	$ 25,000,000.0	50,000,000.0
Agreement Amendment Payment Receivable							10,000,000.0			$ 10,000,000.0
Payments in consideration for development services performed							45,000,000.0
Payments in connection with performance of additional studies							48,700,000
Recognized revenues related to non-refundable payment							1,200,000	600,000	3,500,000
Future milestone payment							10,000,000.0	$ 10,000,000.0	$ 10,000,000.0
Chiesi US Agreement
Non-refundable Payment Receivable					25,000,000.0
Additional Amounts Payable To Cover Development Costs					20,000,000.0
Maximum Entitlement Of Development Costs To Cover Per Year					7,500,000
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones					$ 760,000,000.0		$ 735,000,000.0
Chiesi US Agreement \| Maximum
Payment On Net Sales Percentage					40.00%		40.00%
Chiesi US Agreement \| Minimum
Payment On Net Sales Percentage					15.00%		15.00%
Chiesi Ex-US Agreement
Non-refundable Payment Receivable						25,000,000.0
Additional Amounts Payable To Cover Development Costs						25,000,000.0
Maximum Entitlement Of Development Costs To Cover Per Year						10,000,000.0
Agreement Amendment Payment Receivable											$ 10,000,000.0
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones						$ 320,000,000.0
Chiesi Ex-US Agreement \| Maximum
Payment On Net Sales Percentage						35.00%	35.00%
Chiesi Ex-US Agreement \| Minimum
Payment On Net Sales Percentage						15.00%	15.00%
Kirin Holdings Company, Limited [Member]
Recognized revenues related to non-refundable payment				$ 1,000,000.0
Non-Refundable Future Service Payment		$ 1,000,000.0